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中文名稱

重組人白細(xì)胞介素-11(rHuIL-11)

英文名字
Recombinant Human Interleukin-11 (rHuIL-11)
供應(yīng)商
Bioworld
產(chǎn)品貨號
PR1058
產(chǎn)品報價
¥詢價/2ug
產(chǎn)品說明書
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產(chǎn)品新聞
背景資料
Interleukin 11 is a pleiotropic cytokine that was originally detected in the conditioned medium of an IL-1α-stimulated primate bone marrow stromal cell line (PU-34) as a mitogen for the IL-6-responsive murine plasmacytoma cell line T1165. IL-11 was also independently discovered as an adipogenesis inhibitory factor (AGIF). The human IL-11 cDNA encodes a 199 amino acid residue precursor polypeptide with a 21 amino acid residue hydrophobic signal that is processed proteolytically to generate the 178 amino acid residue mature protein. IL-11 contains no cysteine residues or potential glycosylation sites.IL-11 has multiple effects on both hematopoietic and nonhematopoietic cells. Many of the biological effects described for IL-11 overlap those for IL-6. In vitro, IL-11 can synergize with IL-3, IL-4 and SCF to shorten the G0 period of early hematopoietic progenitors. IL-11 also enhances the IL-3-dependent megakaryocyte colony formation. IL-11 has been found to stimulate the T cell dependent development of specific immunoglobulin-secreting B cell.
序列
PGPPPGPPR VSPDPRAELD STVLLTRSLL ADTRQLAAQL RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD LLSYLRHVQW LRRAGGSSLK TLEPELGTLQ ARLDRLLRRL QLLMSRLALP QPPPDPPAPP LAPPSSAWGG IRAAHAILGG LHLTLDWAVR GLLLLKTRL
來源宿主
Escherichia coli.
溶解建議
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <-20
保存建議
This lyophilized preparation is stable at 2-8
其他
Bioworld是專一服務(wù)于生命科學(xué)研究的專業(yè)技術(shù)型企業(yè),Bioworld品牌創(chuàng)立以來擁有10000多種常規(guī)產(chǎn)品現(xiàn)貨,現(xiàn)有8000多種現(xiàn)貨抗體,以及其他IVD原料,蛋白等現(xiàn)貨產(chǎn)品。在細(xì)胞信號通路、免疫學(xué)、蛋白組學(xué)上擁有顯著優(yōu)勢,其抗體產(chǎn)品、生長因子、IVD原料等為生命科學(xué)科研工作者提供了極大的便利
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