- 中文名稱
重組鼠基質(zhì)細(xì)胞衍生物因子-1 α/CXCL 12(rMuSDF—1a/CXCL 12)
- 英文名字
- Recombinant Murine Stromal-Cell Derived
Factor-1 alpha/CXCL12
(rMuSDF-1a/CXCL12)
- 供應(yīng)商
- Bioworld
- 產(chǎn)品貨號
- PR2035
- 產(chǎn)品報價
- ¥詢價/2ug

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- 產(chǎn)品新聞

- 背景資料
- SDF-1α and SDF-1β, members of the chemokine α subfamily that lack the ELR domain, were initially identified using the signal sequence trap cloning strategy from a mouse bone-marrow stromal cell line. These proteins were subsequently also cloned from a human stromal cell line as cytokines that supported the proliferation of a stromal cell-dependent pre-B-cell line. SDF-1α and SDF-1β cDNAs encode precursor proteins of 89 and 93 amino acid residues, respectively. Both SDF-1α and SDF-1β are encoded by a single gene and arise by alternative splicing. The two proteins are identical except for the four amino acid residues that are present in the carboxy-terminus of SDF-1β and absent from SDF-1α. SDF-1/PBSF is highly conserved between species, with only one amino acid substitution between the mature human and mouse proteins. SDF-1/PBSF acts via the chemokine receptor CXCR4 and has been shown to be a chemoattractant for T-lymphocytes, monocytes, pro- and pre- B cells, but not neutrophils. Mice lacking SDF-1 or CXCR4 have been found to have impaired B-lymphopoiesis, myelopoiesis, vascular development, cardiogenesis and abnormal neuronal cell migration and patterning in the central nervous system .
- 序列
- KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK
- 來源宿主
- Escherichia coli.
- 溶解建議
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <-20
- 保存建議
- This lyophilized preparation is stable at 2-8
- 其他
- Bioworld是專一服務(wù)于生命科學(xué)研究的專業(yè)技術(shù)型企業(yè),Bioworld品牌創(chuàng)立以來擁有10000多種常規(guī)產(chǎn)品現(xiàn)貨,現(xiàn)有8000多種現(xiàn)貨抗體,以及其他IVD原料,蛋白等現(xiàn)貨產(chǎn)品。在細(xì)胞信號通路、免疫學(xué)、蛋白組學(xué)上擁有顯著優(yōu)勢,其抗體產(chǎn)品、生長因子、IVD原料等為生命科學(xué)科研工作者提供了極大的便利

- 注意
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該頁面的中文產(chǎn)品信息的翻譯,僅供參考。準(zhǔn)確的產(chǎn)品信息請以廠家的英文說明書為準(zhǔn)。下單前,請瀏覽說明書確認(rèn)。
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