中文名稱

【rmS100b】重組獼猴S100鈣粘結蛋白B

英文名字

Recombinant Rhesus Macaque S100 Calcium Binding Protein B

供應商

ProSpec

產(chǎn)品貨號

PRO-1236

產(chǎn)品報價

￥詢價/1mg   ￥20ug   ￥5ug

產(chǎn)品說明書

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購買方式

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產(chǎn)品新聞

背景資料

S100b is a member of the S100 family of proteins which are a family of EF-hand calcium binding proteins that exist mostly as dimers of the 20 currently identified individual S100 monomers. The S100B homodimer is expressed in cells of the central nervous system， glial cells and in certain peripheral cells e.g. Schwann cells， melanocytes， adipocytes and chondrocytes. S100 proteins are localized either in the cytoplasm or the nucleus of a wide range of cells. S100 proteins are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. There are at least 13 members in the S100 gene family， which are located as a cluster on chromosome 1q21； however， S100b is located at 21q22.3. The determination of S100B in serum levels may be used to monitor the extent of brain injury and malignant melanoma. S100b proteins may have a role in Neurite extension， proliferation of melanoma cells， stimulation of Ca2+ fluxes， inhibition of PKC-mediated phosphorylation， astrocytosis and axonal proliferation， and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of the S100b gene are implicated in several neurological， neoplastic， and other types of diseases， including Alzheimer’s disease， Down’s syndrome， epilepsy， amyotrophic lateral sclerosis， melanoma， and type I diabetes.

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來源宿主

大腸桿菌中重組表達

溶解建議

提供的重組獼猴S100鈣粘合蛋白B產(chǎn)品形式為凍干粉末.建議用無菌處理的18M-cm水溶解重組獼猴S100鈣粘合蛋白B，濃度不低于100ug/ml.后繼實驗過程中可根據(jù)實驗要求進一步稀釋.

保存建議

重組獼猴S100鈣粘合蛋白B產(chǎn)品在室溫保存3周，于-18°C以下長期保存.一旦溶解，于4°C保存2-7天.避免反復凍融

其他

ProSpec 是一家全球著名細胞因子蛋白生產(chǎn)和研發(fā)的公司，具有20多年的生產(chǎn)經(jīng)驗，專注于蛋白（重組及合成）生產(chǎn)研發(fā)。我們的核心產(chǎn)品包括：干擾素、白介素、骨蛋白、腫瘤壞死因子、成纖維生長因子、瘦素、干細胞因子、催乳素、表皮生長因子、胰島素樣生長因子、神經(jīng)生長因子、集落刺激因子、激素、酶、病毒抗原以及各種重組蛋白等。 領先的生產(chǎn)工藝和規(guī)模使其可以提供毫克到克級蛋白，價格優(yōu)于同類公司。絕大部分產(chǎn)品是天然成熟型蛋白，而不含有標簽蛋白。考慮到大部分研究者希望能更靈活地配制蛋白溶液，ProSpec-Tany絕大部分產(chǎn)品沒有添加保護劑或鹽，這就對工藝提出了更高的要求。同時，ProSpec-Tany絕大部分產(chǎn)品為凍干粉，因此易于運輸和保存。

注意

該頁面的中文產(chǎn)品信息的翻譯，僅供參考。準確的產(chǎn)品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。

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