【內(nèi)皮抑素】重組人鈷抑素-Recombinant Human Endostatin代理/參數(shù)/廠家-蛋白標(biāo)準(zhǔn)品-艾美捷科技有限公司

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背景資料: Once a cluster of cancer cells reaches a diameter of about 1–2 mm， it must develop a blood supply in order to grow larger. Given that diffusion is no longer adequate to supply the cancerous cells with oxygen and nutrients and to remove wastes. Therefore， these cells secrete substances that promote the formation of new blood vessels （angiogenesis）， which are vital for the growth and persistence of solid tumors and their metastases.
The production of several angiogenic factors （FGF-a， FGF-b， VEGF and VPF） is upregulated by tumors in order to stimulate angiogenesis. However， numerous malignant tumors also generate inhibitors of angiogenesis which include angiostatin and thrombospondin. The angiogenic phenotype is basically the end result of a net balance between the positive and negative regulators of neovascularization mentioned above. Endostatin’s role is to inhibit endothelial proliferation， therefore it is an effective angiogenesis inhibitor.

溶解建議: Sterile filtered liquid formulation. The recombinant Human Endostatin is formulated with PBS.

保存建議: Endostatin although stable at 4℃ for 30 days， should be stored desiccated below -20℃ for periods greater than 30 days. Please avoid Freeze/Thaw cycles.

其他: ProSpec 是一家全球著名細(xì)胞因子蛋白生產(chǎn)和研發(fā)的公司，具有20多年的生產(chǎn)經(jīng)驗(yàn)，專注于蛋白（重組及合成）生產(chǎn)研發(fā)。我們的核心產(chǎn)品包括：干擾素、白介素、骨蛋白、腫瘤壞死因子、成纖維生長因子、瘦素、干細(xì)胞因子、催乳素、表皮生長因子、胰島素樣生長因子、神經(jīng)生長因子、集落刺激因子、激素、酶、病毒抗原以及各種重組蛋白等。領(lǐng)先的生產(chǎn)工藝和規(guī)模使其可以提供毫克到克級蛋白，價(jià)格優(yōu)于同類公司。絕大部分產(chǎn)品是天然成熟型蛋白，而不含有標(biāo)簽蛋白。考慮到大部分研究者希望能更靈活地配制蛋白溶液，ProSpec-Tany絕大部分產(chǎn)品沒有添加保護(hù)劑或鹽，這就對工藝提出了更高的要求。同時(shí)，ProSpec-Tany絕大部分產(chǎn)品為凍干粉，因此易于運(yùn)輸和保存。