Ang K1-3 is a proteolytic fragment of plasminogen containing the first three kringle structures. A specific inhibitor of endothelial cell growth and angiogenesis. More active relative to kringles 1-4. Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth.
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大腸桿菌中重組表達(dá)
溶解建議
Sterile Filtered White lyophilized (freeze-dried) powder. Lyophilized from a 0.2um filtered concentrated (1.0mg/ml) solution in 20mM NaAc, pH5.5, 4% mannitol. We recommend to briefly centrifuge the vial prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at <-20°C. Further dilutions should be made in appropriate buffered solutions.
保存建議
The lyophilized Angiostatin K1-3 is stable for several weeks at 2-8℃, but should be kept at -20℃ for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8℃. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20℃ to -70℃.
Avoid repeated freeze/thaw cycles.