P504s / AMACR a-methyl-CoA Racemase is an essential enzyme in the b-oxidation of branched-chain fatty acids, it is responsible for the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomers, which are the only stereoisomers that can be degraded via peroxisomal beta-oxidation. High expression of P504s protein is found in prostatic adenocarcinoma but not in benign prostate tissue by immunohistochemical staining in paraffin-ebmbedded tissue. The expression of P504s is also detected in two premalignant lesions of the prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia.
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大腸桿菌中重組表達(dá)
溶解建議
Sterile Filtered clear solution. P504s at 0.1mg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA, 20% Glycerol.
保存建議
Store vial at -20℃ to -80℃. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles.