中文名稱

【因子-】人凝血因子VIII

英文名字

Human Coagulation Factor VIII

供應(yīng)商

ProSpec

產(chǎn)品貨號

PRO-317

產(chǎn)品報價

￥詢價/600IU

產(chǎn)品說明書

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購買方式

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產(chǎn)品新聞

背景資料

Coagulation factor VIII participates in the intrinsic pathway of blood coagulation； factor VIII is a cofactor for factor IXa which， in the presence of Ca+2 and phospholipids， converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein， isoform a， which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein， isoform b， which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A， a common recessive X-linked coagulation disorder.

序列

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來源宿主

人血漿中提取純化

溶解建議

Sterile Filtered White lyophilized （freeze-dried） powder. The lyophilized protein 200IU/ml was lyophilized from a sterile solution containing 1.5% Glycine， 160mM Calcium chloride and 25mM NaCitrate and 25mM NaCl. It is recommended to reconstitute the lyophilized Factor-VIII in sterile 18MΩ-cm H2O at a concentration of 200IU/ml， which can then be further diluted to other aqueous solutions. Make sure that the vial has reached room temperature prior to its reconstitution， otherwise it might precipitate.

保存建議

Lyophilized Factor-VIII although stable at room temperature for 1 week， should be stored desiccated between 2-8℃. Upon reconstitution Factor-VIII should be storedat 4℃.

其他

ProSpec 是一家全球著名細(xì)胞因子蛋白生產(chǎn)和研發(fā)的公司，具有20多年的生產(chǎn)經(jīng)驗，專注于蛋白（重組及合成）生產(chǎn)研發(fā)。我們的核心產(chǎn)品包括：干擾素、白介素、骨蛋白、腫瘤壞死因子、成纖維生長因子、瘦素、干細(xì)胞因子、催乳素、表皮生長因子、胰島素樣生長因子、神經(jīng)生長因子、集落刺激因子、激素、酶、病毒抗原以及各種重組蛋白等。 領(lǐng)先的生產(chǎn)工藝和規(guī)模使其可以提供毫克到克級蛋白，價格優(yōu)于同類公司。絕大部分產(chǎn)品是天然成熟型蛋白，而不含有標(biāo)簽蛋白。考慮到大部分研究者希望能更靈活地配制蛋白溶液，ProSpec-Tany絕大部分產(chǎn)品沒有添加保護(hù)劑或鹽，這就對工藝提出了更高的要求。同時，ProSpec-Tany絕大部分產(chǎn)品為凍干粉，因此易于運(yùn)輸和保存。

注意

該頁面的中文產(chǎn)品信息的翻譯，僅供參考。準(zhǔn)確的產(chǎn)品信息請以廠家的英文說明書為準(zhǔn)。下單前，請瀏覽說明書確認(rèn)。

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