【恩夫韋地】恩夫韋地T-20-Enfuvirtide T-20代理/參數(shù)/廠家-蛋白標(biāo)準(zhǔn)品-艾美捷科技有限公司

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背景資料: Enfuvirtide also called human immunodeficiency fusion inhibitor blocks HIV’s ability to infect healthy CD4 cells. It can reduce the amount of HIV in the blood and increase the number of CD4 cells. Enfuvirtide operates by disrupting the HIV-1 molecular machinery at the final phase of fusion with the target cell， preventing uninfected cells from becoming infected. Enfuvirtide mimics components of the HIV-1 fusion apparatus and displace them， preventing normal fusion. HIV attaches to the host CD4+ cell receptor using the viral protein GP120； upon binding， GP120 deforms allowing the viral protein GP41 to insert itself into the host cell’s plasma membrane. Entry inhibitors bind to GP41 preventing the formation of an entry pore for the capsid of the virus， keeping it out of the cell.

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溶解建議: Sterile Filtered White lyophilized （freeze-dried） powder. The protein （1mg/ml） was lyophilized with no additives. It is recommended to reconstitute the lyophilized Enfuvirtide in sterile 18MΩ-cm H2O not less than 100ug/ml， which can then be further diluted to other aqueous solutions.

保存建議: Lyophilized Enfuvirtide although stable at room temperature for 3 weeks， should be stored desiccated below -18℃. Upon reconstitution Enfuvirtide should be stored at 4℃ between 2-7 days and for future use below -18℃. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles.

其他: ProSpec 是一家全球著名細(xì)胞因子蛋白生產(chǎn)和研發(fā)的公司，具有20多年的生產(chǎn)經(jīng)驗，專注于蛋白（重組及合成）生產(chǎn)研發(fā)。我們的核心產(chǎn)品包括：干擾素、白介素、骨蛋白、腫瘤壞死因子、成纖維生長因子、瘦素、干細(xì)胞因子、催乳素、表皮生長因子、胰島素樣生長因子、神經(jīng)生長因子、集落刺激因子、激素、酶、病毒抗原以及各種重組蛋白等。領(lǐng)先的生產(chǎn)工藝和規(guī)模使其可以提供毫克到克級蛋白，價格優(yōu)于同類公司。絕大部分產(chǎn)品是天然成熟型蛋白，而不含有標(biāo)簽蛋白。考慮到大部分研究者希望能更靈活地配制蛋白溶液，ProSpec-Tany絕大部分產(chǎn)品沒有添加保護劑或鹽，這就對工藝提出了更高的要求。同時，ProSpec-Tany絕大部分產(chǎn)品為凍干粉，因此易于運輸和保存。