Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. Aprotinin is present in blood and in most tissues, with a high concentration in lung. Aprotinin inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins (e.g., CD11b).
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來源宿主
玉米(谷物)中重組表達
溶解建議
Sterile Filtered lyophilized powder. The protein was lyophilized without any additives. It is recommended to reconstitute the Aprotinin in sterile 18MO-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
保存建議
Aprotinin although stable at room temperature for 3 weeks, should be stored at 4℃.