白細(xì)胞相關(guān)免疫球蛋白樣受體(leukocyte associated immunoglobulin like receptor,LAIR)是表達(dá)于多種免疫細(xì)胞上重要受體,它主要功能是抑制效應(yīng)細(xì)胞對靶細(xì)胞殺傷,并在造血細(xì)胞分化、增殖中具有重要調(diào)節(jié)作用.人可溶型LAIR-1(soluble human LAIR-1,shLAIR-1)還與某些疾病病情、病程有一定聯(lián)系.作為一種抑制性受體,糖基化蛋白LAIR1分子量約為32kDa,在人外周血單核淋巴細(xì)胞,如T細(xì)胞、B細(xì)胞、NK細(xì)胞、巨噬以及樹突狀細(xì)胞表面表達(dá).
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來源宿主
大腸桿菌中重組表達(dá)
溶解建議
Sterile filtered colorless solution. The protein (1mg/ml) contains 20mM Tris-HCl (pH7.5) 50mM NaCl and 1mM EDTA.
保存建議
Store at 4℃ if entire vial will be used within 2-4 weeks.
Store, frozen at -20℃ for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.