E-cadherin (uvomorulin, cell-CAM120/80) is a calcium dependent cell adhesion molecule expressed predominately in epithelial tissues. It plays an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Numerous studies have demonstrated that reduction and/or loss of Ecadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis.
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來源宿主
大腸桿菌中重組表達(dá)
溶解建議
Sterile Filtered clear solution. Cadherin-E protein in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
保存建議
Store vial at -20℃ to -80℃. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles.