【LBP】重組人脂多糖結(jié)合蛋白-Recombinant Human Lipopolysaccarid Binding Protein代理/參數(shù)/廠家-蛋白標(biāo)準(zhǔn)品-艾美捷科技有限公司

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背景資料: Lipopolysaccharides （LPS） are a type of glycolipids on the outer cell wall of Gram-negative bacteria. Lipopolysaccharide binding protein （aka LBP） is a plasma protein which facilitates the diffusion of bacterial LPS （endotoxin）. LBP is involved in the acute-phase immunologic response to gram-negative bacterial infections. In cooperation with bactericidal permeability-increasing protein （BPI）， LBP binds LPS and interacts with the CD14 receptor， most likely playing a role in regulating LPS-dependent monocyte responses. LBP belongs to a family of structurally and functionally related proteins， including BPI， plasma cholesteryl ester transfer protein （CETP）， and phospholipid transfer protein （PLTP）. The LBP gene is found on chromosome 20， directly downstream of the BPI gene. LBP catalyzes the transfer of LPS monomers from LPS aggregates to HDL particles， to phospholipid bilayers， and to a binding site on soluble CD14 （sCD14）. sCD14 is capable of speeding up the transfer by receiving an LPS monomer from an LPS aggregate， and then yielding it to an HDL particle， therefore acting as a soluble "shuttle" for an insoluble lipid.

溶解建議: Sterile Filtered White lyophilized （freeze-dried） powder. Recombinant Human LBP was lyophilized from a protein solution （0.25 mg/ml） containing phosphate-buffered saline， pH 7.2. Every 10ug of recombinant human LBP should be reconstituted using 40ul of sterile H2O.

保存建議: Lyophilized LBP Human Recombinant although stable at room temperature for 3 weeks， should be stored desiccated below -18℃. Upon reconstitution LBP should be stored at 4℃ between 2-7 days and for future use below -18℃. Please prevent freeze-thaw cycles.

其他: ProSpec 是一家全球著名細(xì)胞因子蛋白生產(chǎn)和研發(fā)的公司，具有20多年的生產(chǎn)經(jīng)驗(yàn)，專注于蛋白（重組及合成）生產(chǎn)研發(fā)。我們的核心產(chǎn)品包括：干擾素、白介素、骨蛋白、腫瘤壞死因子、成纖維生長因子、瘦素、干細(xì)胞因子、催乳素、表皮生長因子、胰島素樣生長因子、神經(jīng)生長因子、集落刺激因子、激素、酶、病毒抗原以及各種重組蛋白等。領(lǐng)先的生產(chǎn)工藝和規(guī)模使其可以提供毫克到克級(jí)蛋白，價(jià)格優(yōu)于同類公司。絕大部分產(chǎn)品是天然成熟型蛋白，而不含有標(biāo)簽蛋白。考慮到大部分研究者希望能更靈活地配制蛋白溶液，ProSpec-Tany絕大部分產(chǎn)品沒有添加保護(hù)劑或鹽，這就對(duì)工藝提出了更高的要求。同時(shí)，ProSpec-Tany絕大部分產(chǎn)品為凍干粉，因此易于運(yùn)輸和保存。