中文名稱

【SDC4，他的】重組人多配體蛋白擴(kuò)增4，他的標(biāo)簽

英文名字

Recombinant Human Syndecan-4， His Tag

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ProSpec

產(chǎn)品貨號(hào)

PRO-583

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產(chǎn)品新聞

背景資料

Syndecan-4 is a type I integral membrane heparan sulfate proteoglycan （HSPG）， which was originally isolated from cloned rat microvascular endothelial cells as an antithrombin-binding molecule， and is now known to be a member of the syndecan family. Syndecan-4 binds to basic fibroblast growth factor （bFGF）， midkine， and tissue factor pathway inhibitor via its heparan sulfate chains， and is thought to be involved in various biologic functions such as signaling of bFGF， anticoagulation， and focal adhesion formation. A previous study demonstrated that syndecan-4 is expressed in various tissues， and its level of expression in the kidney is stronger than those of other syndecan family members. Thus， syndecan-4 is thought to play certain roles in maintaining renal function. Moreover， it has been reported that proteoglycans， especially sulfated proteoglycans， are involved in organogenesis of the kidney.

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來源宿主

大腸桿菌中重組表達(dá)

溶解建議

Sterile Filtered White lyophilized （freeze-dried） powder. The SDC4 （1 mg/ml） was lyophilized after extensive dialyses against 20mM PBS pH-7.4. It is recommended to reconstitute the lyophilized SDC4 in sterile 18MΩ-cm H2O not less than 100 ug/ml， which can then be further diluted to other aqueous solutions.

保存建議

Lyophilized SDC4 although stable at room temperature for 3 weeks， should be stored desiccated below -18℃. Upon reconstitution SDC4 should be stored at 4℃ between 2-7 days and for future use below -18℃. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles.

其他

ProSpec 是一家全球著名細(xì)胞因子蛋白生產(chǎn)和研發(fā)的公司，具有20多年的生產(chǎn)經(jīng)驗(yàn)，專注于蛋白（重組及合成）生產(chǎn)研發(fā)。我們的核心產(chǎn)品包括：干擾素、白介素、骨蛋白、腫瘤壞死因子、成纖維生長因子、瘦素、干細(xì)胞因子、催乳素、表皮生長因子、胰島素樣生長因子、神經(jīng)生長因子、集落刺激因子、激素、酶、病毒抗原以及各種重組蛋白等。 領(lǐng)先的生產(chǎn)工藝和規(guī)模使其可以提供毫克到克級蛋白，價(jià)格優(yōu)于同類公司。絕大部分產(chǎn)品是天然成熟型蛋白，而不含有標(biāo)簽蛋白。考慮到大部分研究者希望能更靈活地配制蛋白溶液，ProSpec-Tany絕大部分產(chǎn)品沒有添加保護(hù)劑或鹽，這就對工藝提出了更高的要求。同時(shí)，ProSpec-Tany絕大部分產(chǎn)品為凍干粉，因此易于運(yùn)輸和保存。

注意

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