SNAP23 is a non-neuronal SNAP25 protein homologue and a target SNARE ubiquitously expressed on the plasma membrane and other intracellular membranes. SNAP23 is involved in exocytotic membrane fusion in most cells that do not express SNAP-25. SNAP23 is an essential component of the high affinity receptor for the general membrane fusion machinery and an crucial regulator of transport vesicle docking and fusion. SNAP23 is phosphorylated in platelets through cell activation during a protein kinase C-related mechanism at two or more sites. SNAP23, the ubiqitously expressed homologue of SNAP25, interacts directly with ubiquitous kinesin heavy chain (uKHC). SNAP-23 is expressed in human eosinophils and is a candidates for association with VAMP-2 during docking, which is followed by exocytosis.
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來源宿主
大腸桿菌中重組表達(dá)
溶解建議
Sterile Filtered colorless solution. The protein solution contains 20mM Tris-HCl pH-8.
保存建議
SNAP23 although stable 4℃ for 4 weeks, should be stored desiccated below -18℃.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.