【LYN】重組人酪氨酸蛋白激酶LYN-Recombinant Human Cold Inducible RNA Binding Protein代理/參數(shù)/廠家-蛋白標(biāo)準(zhǔn)品-艾美捷科技有限公司

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背景資料: LYN is part of the SRC family of non-receptor protein tyrosine kinases that is predominantly expressed in haematopoietic tissues. LYN is involved in signal transduction from cell surface receptors that lack intrinsic tyrosine kinase activity. LYN is related with several cell surface receptors as well as B cell antigen receptor and immunoglobulin E receptor （FceRI）. LYN is present in the majority of mediastinal B cell lymphomas. LYN amplification is related with malignant mixed tumor of salivary gland. LYN is involved in regulation of lipopolysaccharide priming in neutrophils. LYN inhibits nuclear export of the p53 tumor suppressor in breast neoplasms. LYN is involved in transduction of the TPO proliferative signal in a megakaryocyte cell line. The kinase domain of Lyn plays a role in Lyn trafficking besides catalysis of substrate phosphorylation. LYN is involved in control of proliferation and survival in most B-non-Hodgkin lymphomas.

溶解建議: Sterile Filtered clear solution. LYN is supplied in 50mM Tris-Acetate， pH-7.5， 1mM EDTA and 20% Glycerol.

保存建議: Store at 4℃ if entire vial will be used within 2-4 weeks. Store， frozen at -20℃ for longer periods of time. Please avoid freeze thaw cycles.

其他: ProSpec 是一家全球著名細(xì)胞因子蛋白生產(chǎn)和研發(fā)的公司，具有20多年的生產(chǎn)經(jīng)驗(yàn)，專注于蛋白（重組及合成）生產(chǎn)研發(fā)。我們的核心產(chǎn)品包括：干擾素、白介素、骨蛋白、腫瘤壞死因子、成纖維生長因子、瘦素、干細(xì)胞因子、催乳素、表皮生長因子、胰島素樣生長因子、神經(jīng)生長因子、集落刺激因子、激素、酶、病毒抗原以及各種重組蛋白等。領(lǐng)先的生產(chǎn)工藝和規(guī)模使其可以提供毫克到克級(jí)蛋白，價(jià)格優(yōu)于同類公司。絕大部分產(chǎn)品是天然成熟型蛋白，而不含有標(biāo)簽蛋白。考慮到大部分研究者希望能更靈活地配制蛋白溶液，ProSpec-Tany絕大部分產(chǎn)品沒有添加保護(hù)劑或鹽，這就對(duì)工藝提出了更高的要求。同時(shí)，ProSpec-Tany絕大部分產(chǎn)品為凍干粉，因此易于運(yùn)輸和保存。