MNDA plays a role as a transcriptional activator/repressor in the myeloid lineage and in the granulocyte/monocyte cell-specific response to interferon. MNDA Stimulates the DNA binding of the transcriptional repressor protein YY1. MNDA is identified only in nuclei of cells of the granulocyte-monocyte lineage. A 200-a.a region of human MNDA is remarkably related to a region in the proteins encoded by a family of interferon-inducible mouse genes, MNDA participates in blood cell-specific responses to interferons.
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來源宿主
大腸桿菌中重組表達(dá)
溶解建議
Sterile Filtered colorless solution. The MNDA solution contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT and 10% glycerol.
保存建議
MNDA although stable 4?C for 4 weeks, should be stored desiccated below -18?C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.