PFN2 is a ubiquitous actin monomer-binding protein which is part of the profilin family. PFN2 regulates actin polymerization in response to extra cellular signals. PFN2 binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, while it increases it at low concentrations. PFN2 binds to PIP2, it inhibits the formation of IP3 and DG.
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來源宿主
大腸桿菌中重組表達(dá)
溶解建議
Sterile filtered colorless solution. PFN2 Human solution containing 20mM Trsi HCL pH-8, 1mM DTT and 10% glycerol.
保存建議
PFN2 human although stable at 4℃ for 1 week, should be stored desiccated below -18℃. Please prevent freeze thaw cycles.