RUNX3 is part of the RUNX family that mediates the expression of genes which participate in cellular differentiation and cell cycle progression. RUNX3 heterodimer and the beta subunit form a complex that binds to the core DNA sequence 5’’-PYGPYGGT-3’’ found in several enhancers and promoters, and can either activate or suppress transcription. RUNX3 interacts with additional transcription factors. RUNX3 is a good candidate for gastric cancer tumor suppressor diagnosis.
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來源宿主
大腸桿菌中重組表達
溶解建議
Sterile filtered colorless solution. RUNX3 Human solution containing 20mM Tris HCL pH-8, 0.1M NaCl, & 20% glycerol.
保存建議
RUNX3 Human although stable at 4℃ for 1 week, should be stored desiccated below -18℃. Please prevent freeze thaw cycles.