RAP1A is part of the family of RAS-related proteins which possess 50% amino acid identity with the classical RAS proteins and have various structural characteristics in common. RAP proteins differ from RAS proteins in their 61st amino acid, glutamine in RAS is replaced by threonine in RAP proteins. RAP1A induces morphological reversion of a cell line transformed by a Ras oncogene and counteracts the mitogenic function of Ras, since it can interact with Ras GAPs and RAF in a competitive manner.
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來源宿主
大腸桿菌中重組表達(dá)
溶解建議
Sterile filtered colorless solution. RAP1A Human solution containing 20mM Tris HCL pH-7.5, 5mM DTT, 0.2M NaCl & 40% glycerol.
保存建議
RAP1A Human although stable at 4℃ for 1 week, should be stored desiccated below -18℃. Please prevent freeze thaw cycles.