SLPI is a secreted inhibitor which guards epithelial tissues from serine proteases. SLPI is localized in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. SLPI inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes. SLPI protein has broad-spectrum anti-biotic activity. SLPI is an acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. SLPI prevents elastase-mediated damage to oral and mucosal tissues.
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來源宿主
大腸桿菌中重組表達
溶解建議
Sterile filtered colorless solution. SLPI Human solution containing 20mM Tris HCL pH-8.0, 2mM DTT, 0.1M NaCl & 20% glycerol.
保存建議
SLPI Human although stable at 4℃ for 1 week, should be stored desiccated below -18℃. Please prevent freeze thaw cycles.