-OxiSelect? Nε-(carboxymethyl) lysine (CML) Competitive ELISA Kit代理/參數(shù)/廠家-其它-艾美捷科技有限公司

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背景資料: Oxidative Stress/ Damage->Advanced Glycation End Products->CML Assays (N-epsilon-(Carboxymethyl) Lysine)->CML Competitive ELISA

應(yīng)用類型: Advanced glycation end products (AGE) are formed during the Maillard reaction where reducing carbohydrates react with lysine side chains and N-terminal amino groups of various macromolecules, particularly proteins. The advanced glycation end products can adversely affect the fuction of these macromolecules. One of the most prevalent AGE products, N-epsilon-(Carboxymethyl) Lysine, has been implicated in oxidative stress and vascular damage. The OxiSelect? N-epsilon-(Carboxymethyl) Lysine Competitive ELISA kit specifically detects CML formation with a high level of sensitivity. This is a Competitive ELISA Kit in which the plate is coated with a CML conjugate.? Standards and unknown samples are added to the plate, followed by incubation with the primary antibody. The CML in the unknown samples and the CML attached to the plate compete for the primary antibody. Higher CML content in unknown samples results in more binding of the antibody to the sample, and thus less antibody binds to the plate. Since the antibody bound to the sample is washed away, higher CML content in samples correlates with a lower signal.

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保存建議: Cell Biolabs公司位于美國(guó)加利福尼亞州南部重要的工業(yè)城市圣迭戈（San Diego），是著名的細(xì)胞學(xué)試劑品牌，作為最前沿的細(xì)胞學(xué)分析檢測(cè)試劑盒生產(chǎn)商，為生物技術(shù)和研究類客戶提供最好的基于細(xì)胞功能研究以及疾病等方面的高端產(chǎn)品和技術(shù)服務(wù)。產(chǎn)品主要涵蓋細(xì)胞研究、細(xì)胞信號(hào)通路和蛋白質(zhì)生物學(xué)、代謝研究、病原體和毒素、干細(xì)胞研究等領(lǐng)域。全球眾多大學(xué)、政府研究機(jī)構(gòu)、生物、制藥企業(yè)的科研實(shí)驗(yàn)室均在使用Cell Biolabs的產(chǎn)品。