- 中文名稱
Epstein-Barr Nuclear Antigen, Human, IgM, BioAssay ELISA Kit (EBNA)
- 英文名字
- Epstein-Barr Nuclear Antigen, Human, IgM, BioAssay ELISA Kit (EBNA)
- 供應(yīng)商
- USBiological
- 產(chǎn)品貨號
- T8171-92G
- 產(chǎn)品報價
- ￥1/1Kit
- 產(chǎn)品說明書
- 點(diǎn)擊查看
- 購買方式
- 銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系400-6800-868
- 產(chǎn)品新聞
- 背景資料
- 產(chǎn)品描述
- The United States Biological Epstein-Barr Nuclear Antigen, Human, IgM, BioAssay ELISA Kit is intended for the detection of IgM antibody to Epstein Barr Virus Nuclear Antigen-1 in human sera and plasma.Detection of the Epstein-Barr virus was first described in 1964 by Epstein, Achong, and Barr using electron microscopic studies of cultured lymphoblasts derived from patients with Burkitt's lymphoma. EBV is classified as a member of the herpes-virus family based upon it's characteristic morphology. EBV infection may demonstrate a wide spectrum of clinical symptoms. The majority of primary EBV infections are transmitted via saliva, occur during childhood, and are subclinical. In the U.S., 50% of the population demonstrate EBV antibodies before the age of 5 years; 80% by adulthood. Transfusion- associated EBV infections have also been reported3. In young adults, EBV infection may be clinically manifested as Infectious Mononucleosis (IM) with typical symptoms of sore throat, fever, and lymphadenopathy. College students and military personnel are often cited as a high morbidity incidence population for IM.Infection of the target cells leads to two forms of viral cycles; 1) latent, nonproductive and 2) productive, replicative infections. In both cycles, one of the earliest antigens expressed is lymphocyte-detected membrane antigen, a cell-surface antigen recognized by T-cells. It has been well established that most individuals exposed to EBV develop a heterophile antibody response. Expression of EBNA-1 either follows or parallels membrane antigen at 12 to 24 hours post infection. EBNA-1 is found as nonstructural, intranuclear antigen(s), present in all EBV-transformed cell lines as in tumors from Burkitt's and nasopharyngeal carcinoma patients. In the fully productive, replicative cycle, the synthesis of antigen follows EBNA-1. The viral capsid antigen complex (VCA) appears late in the replicative cycle. It has recently become apparent that EBNA-1 is probably not a single antigenic moiety, but a multicomponent antigen complex, on the basis of reactivities of serum from different classes of patients. The major component EBNA-1 has been purified and sequenced in its entirety. Antibody levels of EBNA-1 IgG, are diagnostic in determining acute and convalescent stages in IM IgG antibodies to EBNA-1 are rarely present in acute IM and rise during convalescence. They will rise to a plateau level in three months to a year and will normally persist for life. Kit Components:1. Microtiter Plate: 1x96 wells2. Absorbent Solution: 1X22 ml3. Wash Buffer,10X: 1X100ml4. Tetramethylbenzidine (TMB): 1x15ml5. Enzyme conjugate: 1X12 ml 6. Cut-off Calibrator: 1X150ul7. Negative control: 1X150ul8. Positive control: 1X150ul9. Stop solution:1X12 ml (2 N Hcl) Storage and Stability:Store all components at 4°C. Stable for 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- 產(chǎn)品特點(diǎn)
- 針對Epstein-Barr Nuclear Antigen, Human, IgM, BioAssay ELISA Kit (EBNA)該產(chǎn)品的特點(diǎn)優(yōu)勢，歡迎查閱官網(wǎng)提供的產(chǎn)品說明書。
- 保存建議
- 建議收到Epstein-Barr Nuclear Antigen, Human, IgM, BioAssay ELISA Kit (EBNA)產(chǎn)品后將其置于4°C保存。
- 其他
- Usbiological公司是美國著名的抗體和生化試劑供應(yīng)商，生產(chǎn)世界上種類最多的抗體，用于Western Blot、免疫沉淀、免疫熒光、免疫組化和流式細(xì)胞術(shù)等多種檢測方法。Usbiological公司現(xiàn)已擁有超過50,19234種抗體、抗原和生化產(chǎn)品，為科研用戶提供了諸多超值選擇。
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- 注意
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該頁面的中文產(chǎn)品信息的翻譯，僅供參考。準(zhǔn)確的產(chǎn)品信息請以廠家的英文說明書為準(zhǔn)。下單前，請瀏覽說明書確認(rèn)。
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