中文名稱

Ubc12 蛋白(人) (His標簽)

英文名字

Ubc12 protein(human) (His tag)

供應商

Viva Bioscience

產(chǎn)品貨號

VB2482-100

產(chǎn)品報價

￥3250/100ug

產(chǎn)品說明書

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背景資料

Ubc12, also known as UBE2M, is the major NEDD8 E2 conjugating enzyme and an essential component of the NEDD8 cascade.

Ubc12 is responsible for conjugating activated NEDD8 and mediating its subsequent linkage, via C-terminal isopeptide bond formation, to a number of proteins, including the tumour suppressors p53 and VHL, in addition to its well characterised modification of members of the cullin ubiquitin E3 ligase family. Such modifications allow NEDD8 to play a critical regulatory role in cell proliferation and development, a process closely associated to the ubiquitin-proteasome pathway.

Recombinant human Ubc12 protein expressed with a N-terminal His-tag. Protein has utility in NEDDylation reactions and polyNEDD8 chain synthesis.

序列

P61081

來源宿主

溶解建議

0.57 mg/mL

保存建議

其他

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注意

該頁面的中文產(chǎn)品信息的翻譯，僅供參考。準確的產(chǎn)品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。

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