中文名稱

Tetra-泛素蛋白 (Ub4,線性的)

英文名字

Tetra-ubiquitinprotein (Ub4, linear)

供應(yīng)商

Viva Bioscience

產(chǎn)品貨號

VB2572-100

產(chǎn)品報價

￥1625/100ug

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背景資料

ddition to lysine-linked polyubiquitin chains the amino terminus of ubiquitin can be used to form head-to-tail polyubiquitin chains, in which the C-terminal Gly of one ubiquitin is conjugated to the N-terminal Met of an adjacent ubiquitin. Such linear polyubiquitin chains are structurally similar to Lys63-linked polyubiquitin, despite the chemical differences between the two linkage types.

Several ubiquitin polygenes are encoded in eukaryotic cells and undergo post-translational processing to generate the cellular source of free ubiquitin monomers. However, linear polyubiquitin chains have been shown to be assembled in vitro by an E3 ligase complex, known as the linear ubiquitin chain assembly complex (LUBAC), and ubiquitin binding domains (UBDs) with a preference for linear polyubiquitin have been identified in a number of proteins. A possible role for linear polyubiquitin modification in NF-

序列

P0CG47

來源宿主

溶解建議

N/A

保存建議

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注意

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