中文名稱

Gankyrin 蛋白(人) (His標簽)

英文名字

Gankyrin protein(human) (His tag)

供應(yīng)商

Viva Bioscience

產(chǎn)品貨號

VB2648-50

產(chǎn)品報價

￥2125/50ug

產(chǎn)品說明書

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背景資料

Gankyrin is an oncoprotein with potent cell cycle and apoptotic properties that is overexpressed in hepatocarcinogenesis and in hepatocellular carcinomas.It is known to play a role in theregulation of the phosphorylation of the retinoblastoma protein by CDK4, and to enhance the ubiquitinylation of p53 by MDM2. Gankyrin has also been shown to be a component of the 26S proteasome. This suggests a biochemical pathway by which gankyrin may not only control the rate of p53 ubiquitinylation through MDM2 but may also act as an adaptor protein that delivers p53 to the 26S proteasome for degradation.

Recombinant human gankyrin protein expressed with a N-terminal His-tag.

序列

O75832

來源宿主

溶解建議

1 mg/mL

保存建議

其他

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注意

該頁面的中文產(chǎn)品信息的翻譯，僅供參考。準確的產(chǎn)品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。

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