中文名稱

二泛素蛋白 (Ub2, K48-linked)

英文名字

Di-ubiquitinprotein (Ub2, K48-linked)

供應(yīng)商

Viva Bioscience

產(chǎn)品貨號

VB3044-100

產(chǎn)品報價

￥2250/100ug

產(chǎn)品說明書

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購買方式

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背景資料

Di-ubiquitin (Ub2, K48-linked) was synthesised enzymatically, using wild type ubiquitin for the proximal ubiquitin and K48R ubiquitin for the distal ubiquitin, and purified by ion exchange chromatography. Specifically linked di-ubiquitins have utility as substrates for investigating deubiquitinating enzyme (DUB) activity and polyubiquitin chain processing selectivity and in the study of ubiquitin binding and recognition in ubiquitin signalling associated processes.

K48-linked polyubiquitin molecules are key regulators of protein degradation mediated by the proteasome.

Modification of cellular proteins with polyubiquitin chains occurs in a wide range of signalling pathways and is tightly regulated in order to ensure cellular homeostasis. The function, processing and ultimate fate of polyubiquitinylated proteins is thought to be determined by the nature of the linkage between adjacent ubiquitin molecules in the polyubiquitin chain.

序列

P0CG47

來源宿主

?

溶解建議

2.5mg/mL

保存建議

其他

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注意

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