This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.
應(yīng)用類型
WB
免疫原
PMS1
來源宿主
兔
反應(yīng)性
人
保存建議
建議收到該PMS1 Homolog 1, Mismatch Repair System Component (PMS1) Antibody產(chǎn)品后,儲存溫度為-20°C。避免重復(fù)凍融