NANOG Antibody is a Mouse against Human. NANOG is a multidomain homeobox transcription factor which functions to maintain the undifferentiated state of pluripotent stem cells. NANOG expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53.
應(yīng)用類型
ELISA, WB, IHC
免疫原
Homeobox Protein NANOG (NANOG)
來源宿主
小鼠
反應(yīng)性
人
保存建議
建議收到該Homeobox Protein NANOG (NANOG) Antibody產(chǎn)品后,儲存溫度為-20°C。避免重復(fù)凍融