GR（Phospho-Ser 211）DNA結(jié)合ELISA試劑盒-GR (Phospho-Ser211) DNA-Binding ELISA Kit代理/參數(shù)/廠家-ELISA試劑盒-艾美捷科技有限公司

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背景資料: This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175).

產(chǎn)品描述: 該GR (Phospho-Ser211) DNA-Binding ELISA Kit的產(chǎn)品描述請參考該產(chǎn)品的說明書

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