May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1). Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth.
產(chǎn)品描述
該TXNIP ELISA Kit (Rat)的產(chǎn)品描述請參考該產(chǎn)品的說明書
產(chǎn)品特點(diǎn)
ELISA試劑盒
保存建議
Store as indicated in product manual.
其他
Aviva Systems Biology總部位于加利福尼亞州圣迭戈,在中國北京設(shè)有辦公室,專注于為研究需求提供多克隆和單克隆抗體、ELISA試劑盒、蛋白質(zhì)和定制服務(wù)。Aviva Systems Biology生產(chǎn)了24,000種經(jīng)過驗證的多克隆抗體,并提供近20,000種ELISA試劑盒,定制實驗室服務(wù)包括蛋白表達(dá)和純化、抗體開發(fā),以及ELISA的開發(fā)、驗證和生產(chǎn)。Aviva Systems Biology為與獨(dú)特物種和靶標(biāo)相關(guān)的研究提供獨(dú)特工具,研究領(lǐng)域包括轉(zhuǎn)錄因子、癌癥、心血管、細(xì)胞生物學(xué)、DNA損傷和修復(fù)、表觀遺傳學(xué)、信號轉(zhuǎn)導(dǎo)、細(xì)胞分化、干細(xì)胞生物學(xué)等等。