SOCS3 ELISA試劑盒 (Rat)-SOCS3 ELISA Kit (Rat)代理/參數(shù)/廠家-ELISA試劑盒-艾美捷科技有限公司

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背景資料: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS3 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway. Inhibits cytokine signal transduction by binding to tyrosine kinase receptors including gp130, LIF, erythropoietin, insulin, IL12, GCSF and leptin receptors. Binding to JAK2 inhibits its kinase activity. Suppresses fetal liver erythropoiesis. Regulates onset and maintenance of allergic responses mediated by T-helper type 2 cells. Regulates IL-6 signaling in vivo. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to recognize IL6ST (By similarity).

其他: Aviva Systems Biology總部位于加利福尼亞州圣迭戈，在中國北京設(shè)有辦公室，專注于為研究需求提供多克隆和單克隆抗體、ELISA試劑盒、蛋白質(zhì)和定制服務(wù)。Aviva Systems Biology生產(chǎn)了24,000種經(jīng)過驗證的多克隆抗體，并提供近20,000種ELISA試劑盒，定制實驗室服務(wù)包括蛋白表達和純化、抗體開發(fā)，以及ELISA的開發(fā)、驗證和生產(chǎn)。Aviva Systems Biology為與獨特物種和靶標相關(guān)的研究提供獨特工具，研究領(lǐng)域包括轉(zhuǎn)錄因子、癌癥、心血管、細胞生物學(xué)、DNA損傷和修復(fù)、表觀遺傳學(xué)、信號轉(zhuǎn)導(dǎo)、細胞分化、干細胞生物學(xué)等等。