中文名稱(chēng)

Recombinant rat Ephrin-A5

英文名字

Recombinant rat Ephrin-A5

供應(yīng)商

Aviva Systems Biology

產(chǎn)品貨號(hào)

aviva-OPCA00075-1MG

產(chǎn)品報(bào)價(jià)

￥詢(xún)價(jià)/1mg

產(chǎn)品說(shuō)明書(shū)

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產(chǎn)品新聞

背景資料

Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Induces compartmentalized signaling within a caveolae-like membrane microdomain when bound to the extracellular domain of its cognate receptor. This signaling event requires the activity of the Fyn tyrosine kinase. Activates the EPHA3 receptor to regulate cell-cell adhesion and cytoskeletal organization. With the receptor EPHA2 may regulate lens fiber cells shape and interactions and be important for lens transparency maintenance. May function actively to stimulate axon fasciculation. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion (By similarity).

序列

該Recombinant rat Ephrin-A5的序列請(qǐng)參考該產(chǎn)品的說(shuō)明書(shū)

來(lái)源宿主

該Recombinant rat Ephrin-A5的來(lái)源宿主請(qǐng)參考該產(chǎn)品的說(shuō)明書(shū)

溶解建議

該Recombinant rat Ephrin-A5的溶解建議請(qǐng)參考該產(chǎn)品的說(shuō)明書(shū)

保存建議

該Recombinant rat Ephrin-A5的保存建議請(qǐng)參考該產(chǎn)品的說(shuō)明書(shū)

其他

Aviva Systems Biology總部位于加利福尼亞州圣迭戈，在中國(guó)北京設(shè)有辦公室，專(zhuān)注于為研究需求提供多克隆和單克隆抗體、ELISA試劑盒、蛋白質(zhì)和定制服務(wù)。Aviva Systems Biology生產(chǎn)了24,000種經(jīng)過(guò)驗(yàn)證的多克隆抗體，并提供近20,000種ELISA試劑盒，定制實(shí)驗(yàn)室服務(wù)包括蛋白表達(dá)和純化、抗體開(kāi)發(fā)，以及ELISA的開(kāi)發(fā)、驗(yàn)證和生產(chǎn)。Aviva Systems Biology為與獨(dú)特物種和靶標(biāo)相關(guān)的研究提供獨(dú)特工具，研究領(lǐng)域包括轉(zhuǎn)錄因子、癌癥、心血管、細(xì)胞生物學(xué)、DNA損傷和修復(fù)、表觀遺傳學(xué)、信號(hào)轉(zhuǎn)導(dǎo)、細(xì)胞分化、干細(xì)胞生物學(xué)等等。

注意

該頁(yè)面的中文產(chǎn)品信息的翻譯，僅供參考。準(zhǔn)確的產(chǎn)品信息請(qǐng)以廠家的英文說(shuō)明書(shū)為準(zhǔn)。下單前，請(qǐng)瀏覽說(shuō)明書(shū)確認(rèn)。

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