Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).
序列
該ICOS Recombinant Protein (Rat)的序列請參考該產(chǎn)品的說明書
來源宿主
該ICOS Recombinant Protein (Rat)的來源宿主請參考該產(chǎn)品的說明書
溶解建議
該ICOS Recombinant Protein (Rat)的溶解建議請參考該產(chǎn)品的說明書
保存建議
該ICOS Recombinant Protein (Rat)的保存建議請參考該產(chǎn)品的說明書
其他
Aviva Systems Biology總部位于加利福尼亞州圣迭戈,在中國北京設有辦公室,專注于為研究需求提供多克隆和單克隆抗體、ELISA試劑盒、蛋白質和定制服務。Aviva Systems Biology生產(chǎn)了24,000種經(jīng)過驗證的多克隆抗體,并提供近20,000種ELISA試劑盒,定制實驗室服務包括蛋白表達和純化、抗體開發(fā),以及ELISA的開發(fā)、驗證和生產(chǎn)。Aviva Systems Biology為與獨特物種和靶標相關的研究提供獨特工具,研究領域包括轉錄因子、癌癥、心血管、細胞生物學、DNA損傷和修復、表觀遺傳學、信號轉導、細胞分化、干細胞生物學等等。