中文名稱

N，N-二甲基-D-赤型-神經(jīng)鞘氨醇（磷酸激酶C的抑制劑）

英文名字

N,N-Dimethyl-D-erythro-sphingosine (Inhibitor of Phosphokinase C)

供應(yīng)商

Matreya

產(chǎn)品貨號

1320-1

產(chǎn)品報價

￥詢價/1mL

產(chǎn)品說明書

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購買方式

銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金,在線支付寶及網(wǎng)銀支付,或直接與我們電話聯(lián)系400-6800-868

產(chǎn)品新聞

背景資料

N,N-Dimethylsphingosine is a potent and specific inhibitor of sphingosine kinase, the key enzyme in the phosphorylation of sphingosine to sphingosine-1-phosphate. It has also been reported to inhibit protein kinase C (another enzyme that is responsible for phosphorylating amino acids) in certain types of cells.1 It induces apoptosis (including in a number of cancer cell lines), possibly due to the inhibition of sphingosine-1-phosphate synthesis and the resulting increase in ceramides. It acts as a stereospecific enhancer for epidermal growth factor receptor kinase.2 At very low doses N,N-dimethylsphingosine protects the heart against ischemia/reperfusion injury due to its activating sphingosine kinase (via PKCε) which is critical for myocardial ischemic preconditioning.3 It can help prevent neointimal hyperplasia, which may be the result of inhibiting ERK-1/2 and Akt signalling, and modulation of smooth muscle growth.4

產(chǎn)品描述

N,N-Dimethylsphingosine

產(chǎn)品形式

該N，N-二甲基-D-赤型-神經(jīng)鞘氨醇（磷酸激酶C的抑制劑）產(chǎn)品為液體形式

保存建議

對于本產(chǎn)品，我們推薦使用-20℃藍(lán)冰低溫進(jìn)行運輸。在您收到貨物后，我們建議在-20℃溫度下冷凍保存，溶解使用說明請參考本品說明書。

其他

Matreya LLC是一家脂質(zhì)生化公司，致力于開發(fā)和制造高質(zhì)量的脂質(zhì)和生物化學(xué)品。Matreya在化學(xué)合成以及天然產(chǎn)物提取和純化方面經(jīng)驗豐富，生產(chǎn)出的產(chǎn)品具有最佳純度。 Matreya產(chǎn)品線包括一系列鞘脂、糖脂、鞘糖脂、脂肪酸和酯、甾醇和維生素E異構(gòu)體（生育酚和生育三烯酚）。專長是生產(chǎn)高純度鞘氨醇、神經(jīng)酰胺、硫酸酯、神經(jīng)節(jié)苷脂、酶抑制劑、生育酚和生育三烯酚。是全球提供脂質(zhì)產(chǎn)品最全的供應(yīng)商之一。產(chǎn)品涉及生物化學(xué)、制藥、微生物學(xué)、食品和農(nóng)業(yè)等研究領(lǐng)域。

注意

該頁面的中文產(chǎn)品信息的翻譯，僅供參考。準(zhǔn)確的產(chǎn)品信息請以廠家的英文說明書為準(zhǔn)。下單前，請瀏覽說明書確認(rèn)。

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