中文名稱

神經酰胺（羥基）

英文名字

Ceramides (hydroxy)

供應商

Matreya

產品貨號

1323-50

產品報價

￥詢價/50mg

產品說明書

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購買方式

銀行轉賬、電匯、支票、現(xiàn)金,在線支付寶及網銀支付,或直接與我們電話聯(lián)系400-6800-868

產品新聞

背景資料

Ceramide is a fatty acid amide of sphingosine. This product contains ceramides with mostly 2-hydroxy fatty acids (alphahydroxy fatty acids). 2-hydroxy fatty acid ceramides are especially abundant in nervous and epidermal cells. These ceramides are important for the permeability barrier function of epidermis and the lipid organization in membranes. The 2- hydroxylation is catalyzed by fatty acid 2-hydroxylase (FA2H or fatty acid alpha-hydroxylase). Ceramide functions as a precursor in the synthesis of sphingomyelin, glycosphingolipids, and of free sphingosine and fatty acids. The sphingosine can be phosphorylated to form sphingosine-1-phosphate. Two of ceramide’s metabolites, sphingosine-1-phosphate and glucosylceramide, produce cell proliferation and other cellular functions.1 Ceramide exerts numerous biological effects, including induction of cell maturation, cell cycle arrest, terminal cell differentiation, cell senescence, and cell death.2 Because of these effects ceramide has been investigated for its use in cancer treatment and many potential approaches to cancer therapy have been presented.3 Other effects include producing reactive oxygen in mitochondria (followed by apoptosis) and stimulating phosphorylation of certain proteins (especially mitogen activated protein). It also stimulates some protein phosphatases (especially protein phosphatase 2A) making it an important controller of protein activity. Ceramides with short side chains have been shown to enter easily into cells where they are biologically active. Ceramides with longer side chains also enter cells if dissolved in dodecane-isopropanol first.

產品描述

Ceramides, mostly with hydroxy acyl groups

產品形式

該神經酰胺（羥基）產品為固體形式

保存建議

對于本產品，我們推薦使用-20℃藍冰低溫進行運輸。在您收到貨物后，我們建議在-20℃溫度下冷凍保存，溶解使用說明請參考本品說明書。

其他

Matreya LLC是一家脂質生化公司，致力于開發(fā)和制造高質量的脂質和生物化學品。Matreya在化學合成以及天然產物提取和純化方面經驗豐富，生產出的產品具有最佳純度。 Matreya產品線包括一系列鞘脂、糖脂、鞘糖脂、脂肪酸和酯、甾醇和維生素E異構體（生育酚和生育三烯酚）。專長是生產高純度鞘氨醇、神經酰胺、硫酸酯、神經節(jié)苷脂、酶抑制劑、生育酚和生育三烯酚。是全球提供脂質產品最全的供應商之一。產品涉及生物化學、制藥、微生物學、食品和農業(yè)等研究領域。

注意

該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。

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