中文名稱

7-氧代膽固醇| SC-4722 |Δ5-膽固醇-3β-ol-7-one；3β-hydroxy-cholest-5-en-7-one

英文名字

7-oxo Cholesterol|SC-4722|Δ5-Cholesterol-3β-ol-7-one; 3β-hydroxy-cholest-5-en-7-one

供應(yīng)商

Cayman Chemical

產(chǎn)品貨號(hào)

16339-10

產(chǎn)品報(bào)價(jià)

￥詢價(jià)/10mg

產(chǎn)品說明書

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購買方式

銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系400-6800-868

產(chǎn)品新聞

背景資料

7-keto Cholesterol is a bioactive sterol that can affect cholesterol homeostasis, membrane properties and cell survival.{26766,26765} It strongly inhibits cytochrome P450 7A1 (CYP7A1), the cholesterol 7α-hydroxylase, with an IC50 = ~ 1 μM.{26765} 7-keto Cholesterol can be produced by oxidation of cholesterol associated with ethanol-mediated lipid peroxidation or photodamage.{26762,26763,26764} It can also be derived enzymatically by oxidation of 7-dehydrocholesterol, the immediate precursor of cholesterol, by CYP7A1, while 11β-hydroxysteroid dehydrogenase type 1 stimulates its reduction.{26765,26761} 7-keto Cholesterol is a major oxysterol component of oxidized LDL.{26766,5829} This compound can be used as a standard in the determination of cholesterol derivatives by GC-MS or HPLC.

產(chǎn)品描述

A bioactive sterol that can affect cholesterol homeostasis, membrane properties and cell survival; inhibits CYP7A1 with an IC50 = ~ 1 μM; can be used as a standard in the determination of cholesterol derivatives by GC-MS or HPLC

產(chǎn)品形式

A crystalline solid

保存建議

建議您在收到Cayman Chemical品牌的7-keto Cholesterol (10 mg)產(chǎn)品后置于-20度保存，產(chǎn)品有效期為730天.

其他

Cayman Chemical向全球科學(xué)工作者提供多研究領(lǐng)域的生化、免疫試劑和分析試劑盒，其產(chǎn)品被廣泛應(yīng)用于腫瘤、氧化氮、神經(jīng)學(xué)、凋亡、氧化性損傷、內(nèi)分泌學(xué)等不同研究領(lǐng)域.Cayman Chemical可提供用于檢測(cè)的特色試劑盒，如：類花生酸類物質(zhì)、游離的生物標(biāo)志、環(huán)核苷、激素及氧化氮等；也提供多種高質(zhì)量試劑，包括：類花生酸類物質(zhì)、氧化氮試劑及許多相關(guān)脂質(zhì)、脂肪酸、酶和抗體.作為Cayman Chemical在中國的區(qū)域總代理，艾美捷科技有限公司將為中國客戶提供最全面的Cayman Chemical產(chǎn)品以及客戶訂制化服務(wù).

注意

該頁面的中文產(chǎn)品信息的翻譯，僅供參考。準(zhǔn)確的產(chǎn)品信息請(qǐng)以廠家的英文說明書為準(zhǔn)。下單前，請(qǐng)瀏覽說明書確認(rèn)。

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