N-（30-Linoleoyloxy-triacontanoyl）-鞘氨醇-N-(30-Linoleoyloxy-triacontanoyl)-sphingosine代理/參數(shù)/廠家-標(biāo)準(zhǔn)品（生化）-艾美捷科技有限公司

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背景資料: This product is a high purity omega-esterified ceramide that is ideal as a standard and for studies involving skin-barrier lipids. It is found almost exclusively in the epidermal layer, especially in the stratum corneum. The stratum corneum is the outermost cellular layer of the epidermis and functions as the permeability barrier in mammals. It contains 12 extractable ceramide fractions containing sphingosine, 6-hydroxysphingosine, dihydrosphingosine and phytosphingosine bases. The omega-esterified ceramides are formed from glucosylceramide and sphingomyelin in special lamellar bodies in epidermal cells from which they are excreted into the extracellular domain of the outermost cell layer of the epidermis. Mammalian skin contains significant amounts of sphingolipids (as much as 50% of the total lipids), particularly very long chain linoleoyl esterified ceramide and glucosylceramide (also called O-acylceramide and O-acylglucosylceramide). These lipids, which are mostly found in the extracellular domains, are vital to the water permeability barrier to prevent lethal loss of water and pathogen invasion. The omega-esterified ceramides can be covalently bound to proteins of the cornified envelope where they form a hydrophobic layer. A deficiency of linoleoyl omega-esterified ceramides is strongly correlated with skin diseases such as psoriasis and atopic dermatitis.

保存建議: 對(duì)于本產(chǎn)品，我們推薦使用-20℃藍(lán)冰低溫進(jìn)行運(yùn)輸。在您收到貨物后，我們建議在-20℃溫度下冷凍保存，溶解使用說(shuō)明請(qǐng)參考本品說(shuō)明書。

其他: Matreya LLC是一家脂質(zhì)生化公司，致力于開(kāi)發(fā)和制造高質(zhì)量的脂質(zhì)和生物化學(xué)品。Matreya在化學(xué)合成以及天然產(chǎn)物提取和純化方面經(jīng)驗(yàn)豐富，生產(chǎn)出的產(chǎn)品具有最佳純度。 Matreya產(chǎn)品線包括一系列鞘脂、糖脂、鞘糖脂、脂肪酸和酯、甾醇和維生素E異構(gòu)體（生育酚和生育三烯酚）。專長(zhǎng)是生產(chǎn)高純度鞘氨醇、神經(jīng)酰胺、硫酸酯、神經(jīng)節(jié)苷脂、酶抑制劑、生育酚和生育三烯酚。是全球提供脂質(zhì)產(chǎn)品最全的供應(yīng)商之一。產(chǎn)品涉及生物化學(xué)、制藥、微生物學(xué)、食品和農(nóng)業(yè)等研究領(lǐng)域。