中文名稱(chēng)

溶血乳糖神經(jīng)酰胺，合成的

英文名字

lyso-Lactosylceramide, synthetic

供應(yīng)商

Matreya

產(chǎn)品貨號(hào)

2088-1

產(chǎn)品報(bào)價(jià)

￥詢(xún)價(jià)/1mg

產(chǎn)品說(shuō)明書(shū)

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購(gòu)買(mǎi)方式

銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金,在線支付寶及網(wǎng)銀支付,或直接與我們電話聯(lián)系400-6800-868

產(chǎn)品新聞

背景資料

lyso-lactosylceramide, synthetic is a fully synthetic standard containing only the most common naturally occurring d18:1 sphingosine isomer. It is ideal as a standard for mass spectroscopy analysis and for in vivo studies. Lactosylceramide is the precursor of many other glycosphingolipids and also functions as a second messenger and protein receptor making it a very important organic molecule. Many cellular processes are dependent on lactosylceramide since it is the substrate for neutral oligoglycosylceramides and gangliosides, all of which have their own vital functions. Lactosylceramide also helps to stabilize the lipid membrane, activate receptor molecules and acts as a receptor for certain bacteria and toxins. In animals, where it is found mostly in epithelial and neuronal cells, it is expressed on neutrophils and macrophages where it binds to toxins and bacteria, which are then engulfed and eliminated. Its role as a second messenger has been found to be vital and dysfunctions in its processes can lead to cancer and inflammation since it is critical to neutrophil activity and in activating anti-inflammatory responses.1 Therefore, it is being studied for its use in cancer therapies and as a therapy for other diseases. Other examples of lactosylceramide second messenger functions are tumor necrosis factor α and platelet-derived growth factor. A deficiency in the enzyme responsible for hydrolyzing the galactose of lactosylceramide leads to lactosylceramidosis, which is characterized by an accumulation of lactosylceramide that causes a primary neurological disorder.2 Lactosylceramide is also important in the activation of platelet/endothelial cell adhesion molecule-1 which causes adhesion and diapedesis of monocytes/lymphocytes.3 In animals neutral lyso-glycosphingolipids occur naturally in small amounts. lyso-Lactosylceramide can release calcium stores from microsomes in the brain cortex and cerabellum.4 Other lyso-glycosphingolipids also release calcium but in a mechanism different from lyso-lactosylceramide.

產(chǎn)品描述

lyso-LC|1-beta-lactosyl-sphing-4-enine|Lactosylsphingosine

產(chǎn)品形式

該溶血乳糖神經(jīng)酰胺，合成的產(chǎn)品為固體形式

保存建議

對(duì)于本產(chǎn)品，我們推薦使用-20℃藍(lán)冰低溫進(jìn)行運(yùn)輸。在您收到貨物后，我們建議在-20℃溫度下冷凍保存，溶解使用說(shuō)明請(qǐng)參考本品說(shuō)明書(shū)。

其他

Matreya LLC是一家脂質(zhì)生化公司，致力于開(kāi)發(fā)和制造高質(zhì)量的脂質(zhì)和生物化學(xué)品。Matreya在化學(xué)合成以及天然產(chǎn)物提取和純化方面經(jīng)驗(yàn)豐富，生產(chǎn)出的產(chǎn)品具有最佳純度。 Matreya產(chǎn)品線包括一系列鞘脂、糖脂、鞘糖脂、脂肪酸和酯、甾醇和維生素E異構(gòu)體（生育酚和生育三烯酚）。專(zhuān)長(zhǎng)是生產(chǎn)高純度鞘氨醇、神經(jīng)酰胺、硫酸酯、神經(jīng)節(jié)苷脂、酶抑制劑、生育酚和生育三烯酚。是全球提供脂質(zhì)產(chǎn)品最全的供應(yīng)商之一。產(chǎn)品涉及生物化學(xué)、制藥、微生物學(xué)、食品和農(nóng)業(yè)等研究領(lǐng)域。

注意

該頁(yè)面的中文產(chǎn)品信息的翻譯，僅供參考。準(zhǔn)確的產(chǎn)品信息請(qǐng)以廠家的英文說(shuō)明書(shū)為準(zhǔn)。下單前，請(qǐng)瀏覽說(shuō)明書(shū)確認(rèn)。

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