瘦素（小鼠、大鼠）ELISA試劑盒-Leptin (mouse, rat) ELISA kit代理/參數(shù)/廠家-免疫學試劑盒-艾美捷科技有限公司

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中文名稱: 瘦素（小鼠、大鼠）ELISA試劑盒

英文名字: Leptin (mouse, rat) ELISA kit

供應商: Bertin Bioreagent

產(chǎn)品貨號: A05176

產(chǎn)品報價: ￥詢價/96wells

產(chǎn)品說明書: 點擊查看

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背景資料: Enzyme ImmunoAssay (EIA) is a technique to detect and quantify antigens (proteins, hormones…) or antibodies in samples. It relies on the ability of an antibody to bind a specific antigen. Either the antibody or the antigen is labelled with an enzyme whose substrate is a chromogen or a fluorogen converted in a measurable product (color or fluorescence).|Enzyme-linked Immunosorbent Assay (ELISA) is a type of EIA using a solid phase (ex: microtiter plate) coated with an antigen immobilizing the molecule to detect. Over the time, scientists have extended the term ELISA to EIAs using an antibody coating the solid phase. That explains why our EIA kits using coated antibodies are also called ELISA kits.|Leptin, the product of the ob (obese) gene, is produced mainly in the adipose tissue, and is considered to play an important role in appetite control, fat metabolism and body weight regulation. The primary effect of leptin appears to be mediated by leptin receptors expressed mainly in the hypothalamus. In humans, leptin levels correlate with body mass index (BMI) and percentage body fat, and are elevated even in obese individuals. Leptin has a dual action; it decreases the appetite and increases energy consumption. Leptin is secreted in circadian fashion with nocturnal rise in both lean and obese patients. Mutations of the ob gene resulting in leptin deficiency are the cause of obesity in the ob/ob mice suggesting that endogenous leptin can normalize body weight. In contrast, human obese subjects may have high levels of leptin, indicating a mechanism of leptin resistance.

產(chǎn)品描述: 酶免疫測定（EIA）是一種檢測和定量樣品中抗原（蛋白質(zhì)、激素等）或抗體的技術(shù)。它依賴于抗體結(jié)合特定抗原的能力。用酶標記抗體或抗原，所述酶的底物是轉(zhuǎn)化成可測量產(chǎn)物（顏色或熒光）的色原或熒光團。|酶聯(lián)免疫吸附測定（ELISA）是使用固相（例如：微量滴定板）上包被有固定分子的抗原以進行檢測。隨著時間的推移，科學家們已經(jīng)將術(shù)語ELISA擴展到使用抗體包被固相的EIA。這就解釋了為什么我們使用包被抗體的EIA試劑盒也被稱為ELISA試劑盒。|瘦素是ob（肥胖）基因的產(chǎn)物，主要在脂肪組織中產(chǎn)生，并且被認為在食欲控制、脂肪代謝和體重調(diào)節(jié)中起重要作用。瘦素的主要作用似乎是由主要在下丘腦中表達的瘦素受體介導的。在人類中，瘦素水平與體重指數(shù)（BMI）和體脂百分比相關(guān)，并且甚至在肥胖個體中也升高。瘦素具有雙重作用;它會降低食欲并增加能量消耗。瘦素是以晝夜節(jié)律的方式分泌的，在瘦和肥胖患者中夜間升高。ob基因突變導致瘦素缺乏是ob/ob小鼠肥胖的原因，表明內(nèi)源性瘦素可以使體重正常化。相比之下，人類肥胖受試者可能具有高水平的瘦素，表明瘦素抗性的機制。

產(chǎn)品特點: 該瘦素（小鼠、大鼠）ELISA試劑盒,Leptin (mouse, rat) ELISA kit產(chǎn)品產(chǎn)品特點詳情查看產(chǎn)品說明書。

保存建議: Store at +4degrees; shelf life 9 months maximum after production

其他: 法國Bertin Technologies公司是一家大型儀器設備及試劑供應商，擁有50多年的歷史，產(chǎn)品涉及衛(wèi)生、環(huán)境、安全甚至軍工等諸多領域。Bertin Bioreagent是Bertin Technologies集團的生物試劑部門，主要是致力于研發(fā)與炎癥，氧化損傷，內(nèi)分泌學，糖尿病，肥胖癥，高血壓，精神藥理學，癌癥，哮喘，朊病毒疾病，藥代動力學和代謝等相關(guān)的化學試劑，蛋白，底物，抗體及檢測試劑盒等產(chǎn)品。 Bertin Instruments是Bertin Technologies集團的儀器部門，其中旗艦產(chǎn)品Precellys系列多功能生物樣品勻漿器是全世界各個實驗室的明星產(chǎn)品，截至目前累計有15000+的引文！