AFABP（人）ELISA試劑盒-AFABP (human) ELISA kit代理/參數(shù)/廠家-免疫學(xué)試劑盒-艾美捷科技有限公司

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中文名稱: AFABP（人）ELISA試劑盒

英文名字: AFABP (human) ELISA kit

供應(yīng)商: Bertin Bioreagent

產(chǎn)品貨號(hào): A05181

產(chǎn)品報(bào)價(jià): ￥詢價(jià)/96wells

產(chǎn)品說明書: 點(diǎn)擊查看

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背景資料: Enzyme ImmunoAssay (EIA) is a technique to detect and quantify antigens (proteins, hormones…) or antibodies in samples. It relies on the ability of an antibody to bind a specific antigen. Either the antibody or the antigen is labelled with an enzyme whose substrate is a chromogen or a fluorogen converted in a measurable product (color or fluorescence).|Enzyme-linked Immunosorbent Assay (ELISA) is a type of EIA using a solid phase (ex: microtiter plate) coated with an antigen immobilizing the molecule to detect. Over the time, scientists have extended the term ELISA to EIAs using an antibody coating the solid phase. That explains why our EIA kits using coated antibodies are also called ELISA kits.|Adipocyte Fatty Acid Binding Protein (AFABP) is a 15 kDa member of the intracellular Fatty Acid Binding Protein (FABP) family, which is known for the ability to bind fatty acids and related compounds.|AFABP is expressed in a tissue specific-manner in differentiated adipocytes and is a critical gene in the regulation of the biological function of these cells. According to some results, AFABP may be involved in mediating obesity-induced alterations in adipocyte gene expression. In macrophages AFABP modulates inflammatory responses and cholesterol ester accumulation, and total or macrophage-specific AFABP deficiency confers dramatic protection against atherosclerosis in the apoE-/- mice. These results indicate a central role for AFABP in the development of major components of the metabolic syndrome through its distinct actions in adipocytes and macrophages. Besides being active within the cell, AFAB appears to be a secreted protein, with unknown functions.

產(chǎn)品描述: 酶免疫測(cè)定（EIA）是一種檢測(cè)和定量樣品中抗原（蛋白質(zhì)、激素等）或抗體的技術(shù)。它依賴于抗體結(jié)合特定抗原的能力。用酶標(biāo)記抗體或抗原，所述酶的底物是轉(zhuǎn)化成可測(cè)量產(chǎn)物（顏色或熒光）的色原或熒光團(tuán)。|酶聯(lián)免疫吸附測(cè)定（ELISA）是使用固相（例如：微量滴定板）上包被有固定分子的抗原以進(jìn)行檢測(cè)。隨著時(shí)間的推移，科學(xué)家們已經(jīng)將術(shù)語ELISA擴(kuò)展到使用抗體包被固相的EIA。這就解釋了為什么我們使用包被抗體的EIA試劑盒也被稱為ELISA試劑盒。|脂肪細(xì)胞脂肪酸結(jié)合蛋白（AFABP）是細(xì)胞內(nèi)脂肪酸結(jié)合蛋白（FABP）家族的15 kDa成員，已知其具有結(jié)合脂肪酸和相關(guān)化合物的能力。| AFABP在分化的脂肪細(xì)胞中以組織特異性方式表達(dá)，并且是調(diào)節(jié)這些細(xì)胞的生物學(xué)功能的關(guān)鍵基因。根據(jù)一些結(jié)果，AFABP可能參與介導(dǎo)肥胖誘導(dǎo)的脂肪細(xì)胞基因表達(dá)的改變。在巨噬細(xì)胞中，AFABP調(diào)節(jié)炎癥反應(yīng)和膽固醇酯積累，并且總的或巨噬細(xì)胞特異性AFABP缺乏在apoE-/-小鼠中賦予對(duì)動(dòng)脈粥樣硬化的顯著保護(hù)。這些結(jié)果表明，AFABP通過其在脂肪細(xì)胞和巨噬細(xì)胞中的獨(dú)特作用在代謝綜合征的主要組分的發(fā)展中發(fā)揮核心作用。除了在細(xì)胞內(nèi)有活性外，AFAB似乎是一種分泌蛋白，功能未知。

產(chǎn)品特點(diǎn): 該AFABP（人）ELISA試劑盒,AFABP (human) ELISA kit產(chǎn)品產(chǎn)品特點(diǎn)詳情查看產(chǎn)品說明書。

保存建議: Store at +4degrees; shelf life 6 months maximum after production

其他: 法國Bertin Technologies公司是一家大型儀器設(shè)備及試劑供應(yīng)商，擁有50多年的歷史，產(chǎn)品涉及衛(wèi)生、環(huán)境、安全甚至軍工等諸多領(lǐng)域。Bertin Bioreagent是Bertin Technologies集團(tuán)的生物試劑部門，主要是致力于研發(fā)與炎癥，氧化損傷，內(nèi)分泌學(xué)，糖尿病，肥胖癥，高血壓，精神藥理學(xué)，癌癥，哮喘，朊病毒疾病，藥代動(dòng)力學(xué)和代謝等相關(guān)的化學(xué)試劑，蛋白，底物，抗體及檢測(cè)試劑盒等產(chǎn)品。 Bertin Instruments是Bertin Technologies集團(tuán)的儀器部門，其中旗艦產(chǎn)品Precellys系列多功能生物樣品勻漿器是全世界各個(gè)實(shí)驗(yàn)室的明星產(chǎn)品，截至目前累計(jì)有15000+的引文！