GFAP（人）ELISA試劑盒-GFAP (human) ELISA kit代理/參數(shù)/廠家-免疫學試劑盒-艾美捷科技有限公司

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背景資料: Enzyme ImmunoAssay (EIA) is a technique to detect and quantify antigens (proteins, hormones…) or antibodies in samples. It relies on the ability of an antibody to bind a specific antigen. Either the antibody or the antigen is labelled with an enzyme whose substrate is a chromogen or a fluorogen converted in a measurable product (color or fluorescence).|Enzyme-linked Immunosorbent Assay (ELISA) is a type of EIA using a solid phase (ex: microtiter plate) coated with an antigen immobilizing the molecule to detect. Over the time, scientists have extended the term ELISA to EIAs using an antibody coating the solid phase. That explains why our EIA kits using coated antibodies are also called ELISA kits.|Glial Fibrillary Acidic Protein (GFAP), is the principal 8-9 nm intermediate filament in mature astrocytes of the Central Nervous System (CNS). The findings showed that GFAP is released after traumatic brain injury severity and outcome into the blood very soon after traumatic brain injury (TBI), and that GFAP is not released after multiple trauma without brain injury. In the CNS following injury, either as a result of trauma, disease, genetic disorders, or chemical insult, astrocytes become reactive and respond in astrogliosis. Astrogliosis is characterized by rapid synthesis of GFAP. GFAP normally increases with age and there is a wide variation in the collection and processing of human brain tissue. GFAP is also an established biomarker of retinal stress.

產(chǎn)品描述: 酶免疫測定（EIA）是一種檢測和定量樣品中抗原（蛋白質(zhì)、激素等）或抗體的技術(shù)。它依賴于抗體結(jié)合特定抗原的能力。用酶標記抗體或抗原，所述酶的底物是轉(zhuǎn)化成可測量產(chǎn)物（顏色或熒光）的色原或熒光團。|酶聯(lián)免疫吸附測定（ELISA）是使用固相（例如：微量滴定板）上包被有固定分子的抗原以進行檢測。隨著時間的推移，科學家們已經(jīng)將術(shù)語ELISA擴展到使用抗體包被固相的EIA。這就解釋了為什么我們使用包被抗體的EIA試劑盒也被稱為ELISA試劑盒。|膠質(zhì)纖維酸性蛋白（GFAP）是中樞神經(jīng)系統(tǒng)（CNS）的成熟星形膠質(zhì)細胞中主要的8-9 nm中間絲。研究結(jié)果表明，GFAP在創(chuàng)傷性腦損傷嚴重程度和結(jié)果后很快釋放到血液中，并且GFAP在沒有腦損傷的多發(fā)性創(chuàng)傷后不釋放。在損傷后的CNS中，無論是由于創(chuàng)傷、疾病、遺傳性疾病還是化學損傷，星形膠質(zhì)細胞變得反應(yīng)性并在星形膠質(zhì)細胞增生中響應(yīng)。星形膠質(zhì)細胞增生的特征是GFAP的快速合成。GFAP通常隨著年齡的增長而增加，并且在人腦組織的收集和處理中存在廣泛的變化。GFAP也是視網(wǎng)膜應(yīng)激的既定生物標志物。

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