未酰化Ghrelin（豬）ELISA試劑盒-Unacylated Ghrelin (pig) ELISA kit代理/參數(shù)/廠家-免疫學(xué)試劑盒-艾美捷科技有限公司

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中文名稱: 未酰化Ghrelin（豬）ELISA試劑盒

英文名字: Unacylated Ghrelin (pig) ELISA kit

供應(yīng)商: Bertin Bioreagent

產(chǎn)品貨號: A05402

產(chǎn)品報價: ￥詢價/96wells

產(chǎn)品說明書: 點擊查看

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背景資料: Enzyme ImmunoAssay (EIA) is a technique to detect and quantify antigens (proteins, hormones…) or antibodies in samples. It relies on the ability of an antibody to bind a specific antigen. Either the antibody or the antigen is labelled with an enzyme whose substrate is a chromogen or a fluorogen converted in a measurable product (color or fluorescence).|Enzyme-linked Immunosorbent Assay (ELISA) is a type of EIA using a solid phase (ex: microtiter plate) coated with an antigen immobilizing the molecule to detect. Over the time, scientists have extended the term ELISA to EIAs using an antibody coating the solid phase. That explains why our EIA kits using coated antibodies are also called ELISA kits.|Bertin Bioreagent’s expertise is to develop analytical tools for biomarkers. As such, in 2004, Bertin Bioreagent launched its first Ghrelin Biomarker assay kits, under the SPI-Bio brand name, as a result of its state-of-the-art R&D research teams. Bertin Bioreagent was the first company providing bioanalytical tools to assay Acylated and Non-acylated Ghrelin with very high sensitivity.|Ghrelin discovered in 1999, is fast becoming an endocrinology target of the millennium. Ghrelin, identified in rat stomach as an endogenous ligand for the GH secretagogue receptor, is mainly produced in stomach, but has been demonstrated in many other organs. In addition to GH-releasing properties and its orexant action, ghrelin could act as an hormone having effects on gastric motility (similarity with the peptide hormone motilin), acidic secretion, cardiovascular action, antiproliferative effects, pancreatic and glucose metabolism function, sleep... Ghrelin gene raises to mRNA prepro-ghrelin of 117 amino acids. This precursor is processed into ghrelin, 28 amino acids (human). Before being secreted, this peptide is octanoylated at Ser 3. This step is essential for biological activity. If the endogenous peptide appears directly related to feeding behaviour, the potential therapeutic importance of this hormone is not restricted to a regulator of food intake but also may be involved osteoporosis somatopaus, infertility and ovulation induction, and some cardiovascular diseases.

產(chǎn)品描述: 酶免疫測定（EIA）是一種檢測和定量樣品中抗原（蛋白質(zhì)、激素等）或抗體的技術(shù)。它依賴于抗體結(jié)合特定抗原的能力。用酶標(biāo)記抗體或抗原，所述酶的底物是轉(zhuǎn)化成可測量產(chǎn)物（顏色或熒光）的色原或熒光團。|酶聯(lián)免疫吸附測定（ELISA）是使用固相（例如：微量滴定板）上包被有固定分子的抗原以進(jìn)行檢測。隨著時間的推移，科學(xué)家們已經(jīng)將術(shù)語ELISA擴展到使用抗體包被固相的EIA。這就解釋了為什么我們使用包被抗體的EIA試劑盒也被稱為ELISA試劑盒。| Bertin Bioreagent的專長是開發(fā)生物標(biāo)志物的分析工具。因此，2004年，Bertin Bioreagent以SPI-Bio品牌推出了其第一個Ghrelin生物標(biāo)志物檢測試劑盒，這是其最先進(jìn)的研發(fā)團隊的結(jié)果。Bertin Bioreagent是第一家提供生物分析工具以非常高的靈敏度測定酰化和非酰化Ghrelin的公司。| Ghrelin于1999年發(fā)現(xiàn)，正迅速成為千年內(nèi)分泌學(xué)的目標(biāo)。Ghrelin在大鼠胃中被鑒定為GH促分泌素受體的內(nèi)源性配體，主要在胃中產(chǎn)生，但已被證明在許多其他器官中產(chǎn)生。除了GH釋放特性和其食欲作用之外，ghrelin可以作為一種激素，對胃運動（與肽激素胃動素相似）、酸性分泌、心血管作用、抗增殖作用、胰腺和葡萄糖代謝功能、睡眠和呼吸等具有影響。Ghrelin基因表達(dá)為117個氨基酸的前Ghrelin原。這種前體被加工成生長素釋放肽，28個氨基酸（人）。在被分泌之前，該肽在Ser 3處被辛酰化。這一步驟對于生物活性至關(guān)重要。如果內(nèi)源性肽與攝食行為直接相關(guān)，則這種激素的潛在治療重要性不僅限于食物攝入的調(diào)節(jié)劑，而且還可能涉及骨質(zhì)疏松癥、不孕癥和排卵誘導(dǎo)以及一些心血管疾病。

產(chǎn)品特點: 該未酰化Ghrelin（豬）ELISA試劑盒,Unacylated Ghrelin (pig) ELISA kit產(chǎn)品產(chǎn)品特點詳情查看產(chǎn)品說明書。

保存建議: Store at -20degrees; shelf life 2 years maximum after production

其他: 法國Bertin Technologies公司是一家大型儀器設(shè)備及試劑供應(yīng)商，擁有50多年的歷史，產(chǎn)品涉及衛(wèi)生、環(huán)境、安全甚至軍工等諸多領(lǐng)域。Bertin Bioreagent是Bertin Technologies集團的生物試劑部門，主要是致力于研發(fā)與炎癥，氧化損傷，內(nèi)分泌學(xué)，糖尿病，肥胖癥，高血壓，精神藥理學(xué)，癌癥，哮喘，朊病毒疾病，藥代動力學(xué)和代謝等相關(guān)的化學(xué)試劑，蛋白，底物，抗體及檢測試劑盒等產(chǎn)品。 Bertin Instruments是Bertin Technologies集團的儀器部門，其中旗艦產(chǎn)品Precellys系列多功能生物樣品勻漿器是全世界各個實驗室的明星產(chǎn)品，截至目前累計有15000+的引文！