- 中文名稱
TNF-α（豬）ELISA試劑盒
- 英文名字
- TNF-alpha (pig) ELISA kit
- 供應(yīng)商
- Bertin Bioreagent
- 產(chǎn)品貨號(hào)
- A05411
- 產(chǎn)品報(bào)價(jià)
- ￥詢價(jià)/96wells
- 產(chǎn)品說(shuō)明書(shū)
- 點(diǎn)擊查看
- 購(gòu)買(mǎi)方式
- 90%產(chǎn)品中國(guó)有現(xiàn)貨庫(kù)存。銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系400-6800-868
- 產(chǎn)品新聞
- 背景資料
- Enzyme ImmunoAssay (EIA) is a technique to detect and quantify antigens (proteins, hormones…) or antibodies in samples. It relies on the ability of an antibody to bind a specific antigen. Either the antibody or the antigen is labelled with an enzyme whose substrate is a chromogen or a fluorogen converted in a measurable product (color or fluorescence).|Enzyme-linked Immunosorbent Assay (ELISA) is a type of EIA using a solid phase (ex: microtiter plate) coated with an antigen immobilizing the molecule to detect. Over the time, scientists have extended the term ELISA to EIAs using an antibody coating the solid phase. That explains why our EIA kits using coated antibodies are also called ELISA kits.|Known as cachectin, the TNF-alpha (Tumor Necrosis Factor-alpha) is a glycoprotein of 156 amino acids produced from a precursor processed by action of a metalloprotease. Isolated for the first time in 1975 by Carswell, it’s a cytokine of the innate immunity.|Interleukin-1 or bacterial endotoxins stimulate the production of TNF-alpha by immune cells (activated macrophages, NK cells, monocytes) and non-immune cells (keratinocytes, vascular smooth muscle cells, and granulosa lutein cells).|The main function of the TNF-alpha is to act as an immunomodulator and as a mediator of infl ammatory responses in the phenomena of host resistance to infection. It allows neutrophils and macrophages recruitment to infectious sites by stimulating the production of adhesion molecules and chemokines (chemotactic cytokines) by endothelial cells. TNFalpha also acts on the hypothalamus to trigger the fever.|Over-production of TNF-alpha has been implicated in a number of pathological conditions including cachexia, septic shock, and autoimmune disorders.
- 產(chǎn)品描述
- 酶免疫測(cè)定（EIA）是一種檢測(cè)和定量樣品中抗原（蛋白質(zhì)、激素等）或抗體的技術(shù)。它依賴于抗體結(jié)合特定抗原的能力。用酶標(biāo)記抗體或抗原，所述酶的底物是轉(zhuǎn)化成可測(cè)量產(chǎn)物（顏色或熒光）的色原或熒光團(tuán)。|酶聯(lián)免疫吸附測(cè)定（ELISA）是使用固相（例如：微量滴定板）上包被有固定分子的抗原以進(jìn)行檢測(cè)。隨著時(shí)間的推移，科學(xué)家們已經(jīng)將術(shù)語(yǔ)ELISA擴(kuò)展到使用抗體包被固相的EIA。這就解釋了為什么我們使用包被抗體的EIA試劑盒也被稱為ELISA試劑盒。|稱為惡病質(zhì)素的TNF-α（腫瘤壞死因子-α）是由金屬蛋白酶作用加工的前體產(chǎn)生的156個(gè)氨基酸的糖蛋白。1975年由Carswell首次分離，是先天免疫的一種細(xì)胞因子。|白介素-1或細(xì)菌內(nèi)毒素刺激免疫細(xì)胞（活化的巨噬細(xì)胞、NK細(xì)胞、單核細(xì)胞）和非免疫細(xì)胞（角質(zhì)形成細(xì)胞、血管平滑肌細(xì)胞和顆粒黃體細(xì)胞）產(chǎn)生TNF-α。| TNF-a的主要功能是在宿主對(duì)感染的抗性現(xiàn)象中充當(dāng)免疫調(diào)節(jié)劑和炎癥反應(yīng)的介體。它通過(guò)刺激內(nèi)皮細(xì)胞產(chǎn)生粘附分子和趨化因子（趨化性細(xì)胞因子），使中性粒細(xì)胞和巨噬細(xì)胞募集到感染部位。TNF α也作用于下丘腦以觸發(fā)發(fā)燒。| TNF-α的過(guò)度產(chǎn)生涉及許多病理學(xué)病癥，包括惡病質(zhì)、敗血性休克和自身免疫性疾病。
- 產(chǎn)品特點(diǎn)
- 該TNF-α（豬）ELISA試劑盒,TNF-alpha (pig) ELISA kit產(chǎn)品產(chǎn)品特點(diǎn)詳情查看產(chǎn)品說(shuō)明書(shū)。
- 保存建議
- Store at +4degrees; shelf life 6 months maximum after production
- 其他
- 法國(guó)Bertin Technologies公司是一家大型儀器設(shè)備及試劑供應(yīng)商，擁有50多年的歷史，產(chǎn)品涉及衛(wèi)生、環(huán)境、安全甚至軍工等諸多領(lǐng)域。Bertin Bioreagent是Bertin Technologies集團(tuán)的生物試劑部門(mén)，主要是致力于研發(fā)與炎癥，氧化損傷，內(nèi)分泌學(xué)，糖尿病，肥胖癥，高血壓，精神藥理學(xué)，癌癥，哮喘，朊病毒疾病，藥代動(dòng)力學(xué)和代謝等相關(guān)的化學(xué)試劑 ，蛋白，底物，抗體及檢測(cè)試劑盒等產(chǎn)品。 Bertin Instruments是Bertin Technologies集團(tuán)的儀器部門(mén)，其中旗艦產(chǎn)品Precellys系列多功能生物樣品勻漿器是全世界各個(gè)實(shí)驗(yàn)室的明星產(chǎn)品，截至目前累計(jì)有15000+的引文！
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- 注意
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該頁(yè)面的中文產(chǎn)品信息的翻譯，僅供參考。準(zhǔn)確的產(chǎn)品信息請(qǐng)以廠家的英文說(shuō)明書(shū)為準(zhǔn)。下單前，請(qǐng)瀏覽說(shuō)明書(shū)確認(rèn)。
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