- 中文名稱
VEGF-A（豬）ELISA試劑盒
- 英文名字
- VEGF-A (pig) ELISA kit
- 供應(yīng)商
- Bertin Bioreagent
- 產(chǎn)品貨號
- A05426
- 產(chǎn)品報(bào)價(jià)
- ￥詢價(jià)/96wells
- 產(chǎn)品說明書
- 點(diǎn)擊查看
- 購買方式
- 90%產(chǎn)品中國有現(xiàn)貨庫存。銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系400-6800-868
- 產(chǎn)品新聞
- 背景資料
- Enzyme ImmunoAssay (EIA) is a technique to detect and quantify antigens (proteins, hormones…) or antibodies in samples. It relies on the ability of an antibody to bind a specific antigen. Either the antibody or the antigen is labelled with an enzyme whose substrate is a chromogen or a fluorogen converted in a measurable product (color or fluorescence).|Enzyme-linked Immunosorbent Assay (ELISA) is a type of EIA using a solid phase (ex: microtiter plate) coated with an antigen immobilizing the molecule to detect. Over the time, scientists have extended the term ELISA to EIAs using an antibody coating the solid phase. That explains why our EIA kits using coated antibodies are also called ELISA kits.|Vascular endothelial growth factor (VEGF-A or VEGF)(1), also known as vascular permeability factor (VPF)(2), has been discovered in 1983. It is a member of the VEGF family that includes in mammals placental growth factor (PLGF), VEGF-B, VEGF-C, and VEGF-D (also known as c-Fos-induced growth factor, FIGF)(1).|VEGF-A is a glycoprotein having several isoforms of 121 to 206 amino acids(1) with a molecular weight from 33 kDa to 57kDa. It is a homodimer stabilised by hydrophobic interactions and by a disulphide bound(3). The monomer structure contains a central antiparallel four-stranded β sheet with a cystine knot at the end (4).|VEGF-A is produced by many cells like fetal tissu, hematopoietic stem cells, epidermal keratinocytes, podocytes of the renal glomerulus, cardiac myocytes, prostatic epithelium, and certain epithelial cells of the adrenal cortex and lung(5). |The main function of the VEGF-A is the angionesis (formation of new capillaries from pre-existing vessels) during the embryogenesis(1) or during re-building of the blood vessel after an injury. It has also some secondary functions in the chemotacxis of macrophages/ granulocytes and in vasodilation (indirectly by NO release).|Due to its main function, overexpression of VEGF-A causes various diseases including cancer.
- 產(chǎn)品描述
- 酶免疫測定（EIA）是一種檢測和定量樣品中抗原（蛋白質(zhì)、激素等）或抗體的技術(shù)。它依賴于抗體結(jié)合特定抗原的能力。用酶標(biāo)記抗體或抗原，所述酶的底物是轉(zhuǎn)化成可測量產(chǎn)物（顏色或熒光）的色原或熒光團(tuán)。|酶聯(lián)免疫吸附測定（ELISA）是使用固相（例如：微量滴定板）上包被有固定分子的抗原以進(jìn)行檢測。隨著時(shí)間的推移，科學(xué)家們已經(jīng)將術(shù)語ELISA擴(kuò)展到使用抗體包被固相的EIA。這就解釋了為什么我們使用包被抗體的EIA試劑盒也被稱為ELISA試劑盒。|血管內(nèi)皮生長因子（VEGF-A或VEGF）（1），也稱為血管通透性因子（VPF）（2），于1983年發(fā)現(xiàn)。它是VEGF家族的成員，在哺乳動(dòng)物中包括胎盤生長因子（PLGF）、VEGF-B、VEGF-C和VEGF-D（也稱為c-Fos誘導(dǎo)的生長因子，F(xiàn)IGF）（1）。| VEGF-A是具有121至206個(gè)氨基酸（1）的幾種同種型的糖蛋白，分子量為33 kDa至57 kDa。它是一種通過疏水相互作用和二硫鍵穩(wěn)定的同源二聚體（3）。單體結(jié)構(gòu)含有中心反平行四鏈β折疊，末端有胱氨酸結(jié)（4）。| VEGF-A由許多細(xì)胞產(chǎn)生，如胎兒組織、造血干細(xì)胞、表皮角質(zhì)形成細(xì)胞、腎小球足細(xì)胞、心肌細(xì)胞、前列腺上皮以及腎上腺皮質(zhì)和肺的某些上皮細(xì)胞（5）。|VEGF-A的主要功能是在胚胎發(fā)生（1）期間或在損傷后血管重建期間的血管新生（從預(yù)先存在的血管形成新的毛細(xì)血管）。它還在巨噬細(xì)胞/粒細(xì)胞的趨化作用和血管舒張（間接通過NO釋放）中具有一些次要功能。|由于其主要功能，VEGF-A的過表達(dá)引起包括癌癥在內(nèi)的各種疾病。
- 產(chǎn)品特點(diǎn)
- 該VEGF-A（豬）ELISA試劑盒,VEGF-A (pig) ELISA kit產(chǎn)品產(chǎn)品特點(diǎn)詳情查看產(chǎn)品說明書。
- 保存建議
- Store at +4degrees; shelf life 6months maximum after production
- 其他
- 法國Bertin Technologies公司是一家大型儀器設(shè)備及試劑供應(yīng)商，擁有50多年的歷史，產(chǎn)品涉及衛(wèi)生、環(huán)境、安全甚至軍工等諸多領(lǐng)域。Bertin Bioreagent是Bertin Technologies集團(tuán)的生物試劑部門，主要是致力于研發(fā)與炎癥，氧化損傷，內(nèi)分泌學(xué)，糖尿病，肥胖癥，高血壓，精神藥理學(xué)，癌癥，哮喘，朊病毒疾病，藥代動(dòng)力學(xué)和代謝等相關(guān)的化學(xué)試劑 ，蛋白，底物，抗體及檢測試劑盒等產(chǎn)品。 Bertin Instruments是Bertin Technologies集團(tuán)的儀器部門，其中旗艦產(chǎn)品Precellys系列多功能生物樣品勻漿器是全世界各個(gè)實(shí)驗(yàn)室的明星產(chǎn)品，截至目前累計(jì)有15000+的引文！
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- 注意
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該頁面的中文產(chǎn)品信息的翻譯，僅供參考。準(zhǔn)確的產(chǎn)品信息請以廠家的英文說明書為準(zhǔn)。下單前，請瀏覽說明書確認(rèn)。
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