GAP檢測試劑盒-GAP Assay Kit代理/參數(shù)/廠家-細胞分析試劑盒-艾美捷科技有限公司

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中文名稱: GAP檢測試劑盒

英文名字: GAP Assay Kit

供應(yīng)商: Cytoskeleton

產(chǎn)品貨號: BK105

產(chǎn)品報價: ￥詢價/KIT80-160assays

產(chǎn)品說明書: 點擊查看

購買方式: Cytoskeleton中國區(qū)現(xiàn)貨中心已經(jīng)建立，大部分產(chǎn)品中國有現(xiàn)貨庫存。銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系400-6800-868

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背景資料: 該GAP檢測試劑盒產(chǎn)品是Cytoskeleton品牌原裝進口，Cytoskeleton品牌是細胞骨架研究專家，專注于生物化學(xué)和細胞過程研究中的純化蛋白和便捷試劑盒開發(fā)與生產(chǎn)。艾美捷作為中國區(qū)域的總代理，是行業(yè)中少有的致力于服務(wù)客戶，幫助客戶，且擁有獨立專業(yè)技術(shù)支持團隊的高科技生物企業(yè)。可以為您提供及時的咨詢響應(yīng)，專業(yè)的產(chǎn)品和解決方案支持，穩(wěn)健快捷的交貨周期，優(yōu)質(zhì)放心的售后服務(wù)。我們致力于為您提供有價值的產(chǎn)品和服務(wù)，在意您的成功！

產(chǎn)品描述: 收到該GAP檢測試劑盒GAP Assay Kit產(chǎn)品后，查看廠家提供的產(chǎn)品說明書詳細介紹。

產(chǎn)品特點: The Ras superfamily of small GTPases (such as Ras, Rho, Rab, Arf and Ran proteins) serve as binary switches cycling between a GDP-bound “OFF state” and a GTP-bound “ON state”, which mediates signals downstream. In cells, the cycling between the two states is mainly controlled by two types of regulatory proteins: the activating Guanine nucleotide Exchange Factors (GEFs) and the inactivating GTPase Activating Proteins (GAPs). Small G-proteins of the Ras superfamily typically have an inrinsic GTPase activity, meaning that after they get activated (GTP-bound) by GEFs, they eventually “turn themselves off”. The intrinsic GTPase rate, however, is normally very slow, so the “automatic” turning off process can take up to hours. Because of the slow intrinsic GTPase activity in most Ras superfamily GTPases, their GAPs are important signaling molecules that function to terminate their signaling. GAPs function by binding to the active, GTP-bound, form of their target G-proteins and greatly stimulating the G-protein’s intrinsic GTPase activity, thereby quickly turning off the G-protein. This GAP assay kit measures the amount of inorganic phosphate (Pi) that is produced as a result of G-protein dependent hydrolysis of GTP to GDP + Pi. The kit contains all the reagents needed for the assay including GTPases, a positive control RhoGAP, carefully optimized buffers and phosphate detection reagent. The assay can be performed in either 96-well plates or in 384-well plates. There is enough reagents for 80 assays (20 for each provided GTPase) in the 96-well format and 160 assays (40 for each provided GTPase) in the 384-well format While the kit comes with Cdc42, Rac1, RhoA and Ras proteins, it can also be used for any other Ras superfamily GTPase. See our G-protein product family web page for other GTPases available from Cytoskeleton.

保存建議: 廠家推薦常溫運輸，收到產(chǎn)品后建議保存于4°C。

其他: Cytoskeleton公司成立于1993年，專注于生物化學(xué)和細胞過程研究中的純化蛋白和便捷試劑盒開發(fā)與生產(chǎn)。公司提供藥物篩選、信號轉(zhuǎn)導(dǎo)、蛋白質(zhì)轉(zhuǎn)錄后修飾（PTM）、細胞骨架研究相關(guān)的系列試劑盒和產(chǎn)品，尤其以細胞骨架相關(guān)研究見長，既能滿足于樣品較少的科學(xué)研究，也可以用于小規(guī)模篩選研究和高通量大規(guī)模篩選研究。此外，公司還提供微管蛋白，肌動蛋白，小G蛋白，GAPs，GEFs等現(xiàn)有產(chǎn)品的藥物篩選服務(wù)。