Signal-Seeker SUMOylation 富集試劑盒（10 assays）-Signal-Seeker SUMOylation Enrichment Kit (10 assays)代理/參數(shù)/廠家-細(xì)胞分析試劑盒-艾美捷科技有限公司

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背景資料: SUMOylation of a target protein is a recently discovered post-translational modification that has been shown to play a critical role in protein
structure and function. Recent proteomic studies have identified hundreds of proteins that are SUMOylated. As SUMO modifications are
relatively new compared to other PTMs, tools to investigate SUMO are not well established. Appropriate lysis buffers, high quality affinity
reagents, and appropriate inhibitors are all critical reagents for effectively studying SUMO modifications. Here we describe a newly developed
Signal-Seeker SUMO 2/3 detection kit (BK162) that rapidly identifies SUMO 2/3 modifications for any target protein. This kit utilizes
optimized buffers and inhibitors to preserve SUMO 2/3 modifications unlike conventional, non-denaturing lysis buffers. Additionally, the
sensitivity of the kit allows for investigation of endogenous and dynamic changes of SUMO 2/3 modifications. Finally, we show that the
BK162 kit allows for SUMO 2/3 detection from both cell culture and tissue. Collectively, these studies highlight the utility of the BK162 kit
to investigate SUMO 2/3 modifications of several target proteins in various applications.

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其他: Cytoskeleton公司成立于1993年，專注于生物化學(xué)和細(xì)胞過程研究中的純化蛋白和便捷試劑盒開發(fā)與生產(chǎn)。公司提供藥物篩選、信號(hào)轉(zhuǎn)導(dǎo)、蛋白質(zhì)轉(zhuǎn)錄后修飾（PTM）、細(xì)胞骨架研究相關(guān)的系列試劑盒和產(chǎn)品，尤其以細(xì)胞骨架相關(guān)研究見長，既能滿足于樣品較少的科學(xué)研究，也可以用于小規(guī)模篩選研究和高通量大規(guī)模篩選研究。此外，公司還提供微管蛋白，肌動(dòng)蛋白，小G蛋白，GAPs，GEFs等現(xiàn)有產(chǎn)品的藥物篩選服務(wù)。