AZDye? 532 NHS Ester? is an amine reactive, yellow emitting dye routinely used to label proteins or antibodies through the primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond.nnAZDye? 532 is a water-soluble, highly photostable, and bright yellow dye with pH insensitive emission from pH 4 to pH 10. The excitation of AZDye? 532 ideally suited for the frequency-doubled Nd:YAG laser line. AZDye? 532 dye conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates often used for generation of stable signal in imaging and flow cytometry.nnAZDye? 532 is structurally identical to Alexa Fluor? 532. Its absorption/emission spectra is a perfect match to spectra of many other fluorescent dyes based on sulfonated rhodamine core, including Alexa Fluor? 532 and CF?532 Dye.nn Alexa Fluor? 532 Dye is a registered trademark of Thermo Fisher Scientific. CF? Dye is a registered trademark of Biotium, Inc
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Click Chemistry Tools(CCT)公司位于美國(guó)亞利桑那州斯科茨代爾(Scottsdale,AZ)。自公司成立以來(lái),一致致力于不斷開(kāi)發(fā)和擴(kuò)展一系列連接產(chǎn)品。他們利用特別新的研究成果研發(fā)生產(chǎn)出新穎的交聯(lián)和標(biāo)記試劑。產(chǎn)品被廣泛用于藥物研發(fā)、癌癥治療以及各類(lèi)診斷技術(shù)等。此外,CCT還可以提供個(gè)性化的定制產(chǎn)品,已滿(mǎn)足不同用戶(hù)的需求。目前CCT的產(chǎn)品線(xiàn)主要包括:Azides(Biotin-Azides)試劑、Bis-sulfone交聯(lián)試劑、DBCO試劑、TCO試劑、Terminal Alkyne試劑、Tetrazine試劑、標(biāo)記試劑盒以及分選用底物等。nFluoroprobes公司位于美國(guó)亞利桑那州斯科茨代爾(Scottsdale, AZ),自成立以來(lái),一直致力于不斷開(kāi)發(fā)一系列的連接(linker)產(chǎn)品。利用特別新的研究成果研發(fā)生產(chǎn)出各類(lèi)新穎的交聯(lián)和標(biāo)記試劑。其產(chǎn)品被廣泛用于藥物研發(fā)與篩選、疾病治療方法和診斷技術(shù)等領(lǐng)域。此外,F(xiàn)luoroprobes還可以根據(jù)客戶(hù)的個(gè)性化需求提供各類(lèi)定制連接產(chǎn)品。代表產(chǎn)品有Classic Fluorescent Dyes, AZDye, Cyanine Dyes, IR Dyes, MB dyes以及一些標(biāo)記試劑盒等。nQuanta Biodesign公司位于美國(guó)中部的俄亥俄州,成立于1997年。也是專(zhuān)注于生產(chǎn)研發(fā)各類(lèi)標(biāo)記產(chǎn)品的品牌之一。其研發(fā)的產(chǎn)品與dPEG技術(shù)相結(jié)合,生產(chǎn)出他們獨(dú)有的專(zhuān)利產(chǎn)品dPEG Building Blocks and Linkers,被廣泛用于細(xì)胞治療和分子診斷等研究領(lǐng)域。另外,還可為廣大科研工作者提供多種化學(xué)修飾試劑以及傳統(tǒng)Liner等。n目前上述三個(gè)品牌都已被被Vectorlabs收購(gòu)并整合到Vectorlabs產(chǎn)品中