中文名稱

Irisin 重組蛋白

英文名字

Irisin Recombinant Protein

供應(yīng)商

ProSci

產(chǎn)品貨號

PSI-92-627

產(chǎn)品報價

￥詢價/0.05mg

產(chǎn)品說明書

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購買方式

銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系400-6800-868

產(chǎn)品新聞

背景資料

Fibronectin type III domain-containing protein 5, the precursor of irisin, is a protein that is encoded by the FNDC5 gene.Human Irisin is synthesized as a 212 amino acid (aa) precursor encoding a type 1 transmembrane protein with a 121 aa extracellular domain (ECD), a 21 aa transmembrane domain, and a 39 aa cytoplasmic domain. The ECD of Irisin contains a fibronectin type III domain and multiple glycosylation sites. The ECD is proteolytically cleaved to release the 112 aa soluble Irisin hormone into circulation.Mature human, mouse share 100% sequence identity.Irisin induces expression of peroxisome proliferatoractivated receptor gamma coactivator 1 alpha (PGC1 alpha) and uncoupling protein1(UCP1), mitochondrialassociated metabolic proteins. Irisin induces the transition of white adipose tissue into more metabolically active beige adipose tissue.Irisin also regulates neuronal cell differentiation and neurite outgrowth in the brain and is involved in the differentiation of osteoblasts.

序列

Asp32-Glu143

來源宿主

人 細(xì)胞

溶解建議

艾美捷溫馨提示:開蓋前,請先離心。廠家建議您，按照該貨號產(chǎn)品的說明書中要求的方式進行溶解和使用。

保存建議

Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.

其他

ProSci Incorporated于1998年成立于美國加州圣地亞哥市,從事抗體等科研試劑的研發(fā)、生產(chǎn)和銷售。產(chǎn)品涵蓋了細(xì)胞凋亡、信號轉(zhuǎn)導(dǎo)、免疫、腫瘤、細(xì)胞生物、神經(jīng)生物、傳染病等領(lǐng)域。ProSci擁有超過30000種單克隆抗體和多克隆抗體。ProSci的抗體大都經(jīng)免疫親和層析純化,具有高純度、高親和力、特異性強等特點,所有的ProSci抗體都經(jīng)過了嚴(yán)格的驗證測試和質(zhì)量控制,已保證高質(zhì)量的產(chǎn)品。此外,ProSci還提供標(biāo)記二抗,重組蛋白,細(xì)胞和組織裂解液,細(xì)胞涂片,組織切片,多肽等產(chǎn)品與抗體配套使用。

注意

該頁面的中文產(chǎn)品信息的翻譯，僅供參考。準(zhǔn)確的產(chǎn)品信息請以廠家的英文說明書為準(zhǔn)。下單前，請瀏覽說明書確認(rèn)。

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