- 中文名稱
LAG3 抗體 [2G8]
- 英文名字
- LAG3 Antibody [2G8]
- 供應(yīng)商
- ProSci
- 產(chǎn)品貨號(hào)
- PSI-RF16082
- 產(chǎn)品報(bào)價(jià)
- ￥詢價(jià)/0.1mg
- 產(chǎn)品說明書
- 點(diǎn)擊查看
- 購(gòu)買方式
- 銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系400-6800-868
- 產(chǎn)品新聞
- 背景資料
- The lymphocyte activation gene-3 (LAG3) is a member of the immunoglobulin superfamily and binds MHC class II with high affinity (1), negatively regulating T-cell function and homeostasis (2). It is expressed in B, T, and NK cells, monocytes, and dendritic cells (3), and acts to regulate T cell expansion (4). LAG3 is also an important immune checkpoint protein, with anti-LAG3 antibodies activating T effector cells and affecting regulatory T cell functions. Furthermore LAG3 appears to act in a synergistic fashion with PD-1/PD-L1, suggesting that a dual antibody approach may prove useful in cancer immunotherapy.
- 應(yīng)用類型
- E, WB, IHC-P, ICC, IF, Flow
- 免疫原
- LAG-3 antibody was raised against the extracellular domain of human LAG-3
- 來源宿主
- 小鼠
- 反應(yīng)性
- 人
- 保存建議
- LAG-3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 其他
- ProSci Incorporated于1998年成立于美國(guó)加州圣地亞哥市,從事抗體等科研試劑的研發(fā)、生產(chǎn)和銷售。產(chǎn)品涵蓋了細(xì)胞凋亡、信號(hào)轉(zhuǎn)導(dǎo)、免疫、腫瘤、細(xì)胞生物、神經(jīng)生物、傳染病等領(lǐng)域。ProSci擁有超過30000種單克隆抗體和多克隆抗體。ProSci的抗體大都經(jīng)免疫親和層析純化,具有高純度、高親和力、特異性強(qiáng)等特點(diǎn),所有的ProSci抗體都經(jīng)過了嚴(yán)格的驗(yàn)證測(cè)試和質(zhì)量控制,已保證高質(zhì)量的產(chǎn)品。此外,ProSci還提供標(biāo)記二抗,重組蛋白,細(xì)胞和組織裂解液,細(xì)胞涂片,組織切片,多肽等產(chǎn)品與抗體配套使用。
- 注意
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該頁(yè)面的中文產(chǎn)品信息的翻譯，僅供參考。準(zhǔn)確的產(chǎn)品信息請(qǐng)以廠家的英文說明書為準(zhǔn)。下單前，請(qǐng)瀏覽說明書確認(rèn)。
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