anti HMGB1 monoclonal antibodynThe mouse monoclonal IgG1 DPH1.1 was generated by injecting C57BL/6 mice with the 17-mer peptide P1 (KGKPDAAKKGVVKAEKS). Hybridomas were generated from splenocytes by standard techniques and tested by ELISA against the immunogen and full-length HMGB1.nnDPH1.1 mAb recognizes all mammalian HMGB1s, including human, mouse and rat. Does not recognize HMGB2.nDPH1.1 mAb can be used for Western blot (WB) and immunohistochemistry (IHC).nDPH1.1 mAb blocks HMGB1-elicited cell migration in trans-well migration assays.nIn vivo, DPH1.1 mAb administered intravenously (220 μg/mouse) blocks recruitment of inflammatory cells to sites of necrosis and infection.nnThis product is intended for research only, and cannot be used on humans.
免疫原
DPH1.1抗HMGB1單克隆抗體查看提供的datasheet
來源宿主
DPH1.1抗HMGB1單克隆抗體查看提供的datasheet
反應性
DPH1.1抗HMGB1單克隆抗體查看提供的datasheet
保存建議
-20
其他
HMGBiotech是一家由HMGB領(lǐng)域的領(lǐng)先科學家Marco E. Bianchi創(chuàng)立的生物技術(shù)公司。nHMGBiotech是HMGB55質(zhì)量控制氧化還原變體的唯一生產(chǎn)商。該公司為活躍在這一有前途的領(lǐng)域的其他研究人員和公司提供試劑、服務(wù)和想法,并幫助Bianchi實驗室(the Bianchi lab)開發(fā)檢測和試劑。